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Multiple LDLR family members act as entry receptors for yellow fever virus

mercredi 29 octobre 2025 par Zhenlu Chong, Sean Hui, Xueer Qiu, Sathvik Palakurty, Alan Sariol, Tomasz Kaszuba, Michael N. Nguyen, Pengfei Li, Saravanan Raju, Paige D. Hall, Christopher A. Nelson, Israel Baltazar-Perez, David A. Price, Paul W. Rothlauf, James E. Crowe, Sean P. J. Whelan, Daisy W. Leung, Gaya K. Amarasinghe, Adam L. Bailey, Daved H. Fremont, Michael S. Diamond

Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09689-2The low-density lipoprotein receptor family members LRP1, LRP4 and VLDLR are entry receptors for yellow fever virus.

Nature

Origins of chromosome instability unveiled by coupled imaging and genomics

mercredi 29 octobre 2025 par Marco Raffaele Cosenza, Alice Gaiatto, Bü?ra Erarslan Uysal, Álvaro Andrades, Nina Luisa Sautter, Marina Simunovic, Michael Adrian Jendrusch, Sonia Zumalave, Tobias Rausch, Aliaksandr Halavatyi, Eva-Maria Geissen, Joshua Lucas Eigenmann, Thomas Weber, Patrick Hasenfeld, Eva Benito, Catherine Stober, Isidro Cortes-Ciriano, Andreas E. Kulozik, Rainer Pepperkok, Jan O. Korbel

Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09632-5Coupling live-cell imaging, machine learning and genomic sequencing, the MAGIC platform enables investigation of the cellular context, mutation rates and triggers of spontaneous chromosomal abnormality formation, shedding (...)

Nature

Energy flows reveal declining ecosystem functions by animals across Africa

mercredi 29 octobre 2025 par Ty Loft, Imma Oliveras Menor, Nicola Stevens, Robert Beyer, Hayley S. Clements, Luca Santini, Seth Thomas, Joseph A. Tobias, Yadvinder Malhi

Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09660-1An ecosystem energetics approach, quantifying trophic energy flows across species, offers a unified framework for linking animal biodiversity loss to changes in ecosystem function and Earth system (...)

Nature

Mechanism of conductance control and neurosteroid binding in NMDA receptors

mercredi 29 octobre 2025 par Hyunook Kang, Ruben Steigerwald, Elijah Z. Ullman, Max Epstein, Srinu Paladugu, Dennis C. Liotta, Stephen F. Traynelis, Hiro Furukawa

Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09695-4Ion-channel conductance levels are controlled by the bending patterns of pore-forming transmembrane helices in the heterotetrameric neuronal channel GluN1a-2B N-methyl-D-aspartate (...)

Nature

Ultrasound-driven programmable artificial muscles

mercredi 29 octobre 2025 par Zhan Shi, Zhiyuan Zhang, Justus Schnermann, Stephan C. F. Neuhauss, Nitesh Nama, Raphael Wittkowski, Daniel Ahmed

Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09650-3A soft artificial muscle with programmable actuation is achieved using microbubble arrays and targeted ultrasound activation, with potential applications in soft robotics, wearable technologies, haptics and biomedical (...)

Nature

Sensory expectations shape neural population dynamics in motor circuits

mercredi 29 octobre 2025 par Jonathan A. Michaels, Mehrdad Kashefi, Jack Zheng, Olivier Codol, Jeffrey Weiler, Rhonda Kersten, Jonathan C. Lau, Paul L. Gribble, Jörn Diedrichsen, J. Andrew Pruszynski

Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09690-9Experiments with human volunteers and macaques show that expectations produced by probabilistic cueing of future sensory inputs shape motor circuit dynamics in order to increase the efficiency of movement (...)

Nature

Helicase-mediated mechanism of SSU processome maturation and disassembly

mercredi 29 octobre 2025 par Olga Buzovetsky, Sebastian Klinge

Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09688-3Structural studies of 16 native yeast ribosomal small subunit processome structures provide insights into the mechanisms governing the transformation into a pre-40S (...)

Nature

A pangenome and pantranscriptome of hexaploid oat

mercredi 29 octobre 2025 par Raz Avni, Nadia Kamal, Lidija Bitz, Eric N. Jellen, Wubishet A. Bekele, Tefera T. Angessa, Petri Auvinen, Oliver Bitz, Brian Boyle, Francisco J. Canales, Craig H. Carlson, Brett Chapman, Harmeet Singh Chawla, Yutang Chen, Dario Copetti, Samara Correia de Lemos, Viet Dang, Steven R. Eichten, Kathy Esvelt Klos, Amit M. Fenn, Anne Fiebig, Yong-Bi Fu, Heidrun Gundlach, Rajeev Gupta, Georg Haberer, Tianhua He, Matthias H. Herrmann, Axel Himmelbach, Catherine J. Howarth, Haifei Hu, Julio Isidro y Sánchez, Asuka Itaya, Jean-Luc Jannink, Yong Jia, Rajvinder Kaur, Manuela Knauft, Tim Langdon, Thomas Lux, Sofia Marmon, Vanda Marosi, Klaus F. X. Mayer, Steve Michel, Raja Sekhar Nandety, Kirby T. Nilsen, Edyta Paczos-Grz?da, Asher Pasha, Elena Prats, Nicholas J. Provart, Adriana Ravagnani, Robert W. Reid, Jessica A. Schlueter, Alan H. Schulman, Taner Z. Sen, Jaswinder Singh, Mehtab Singh, Nick Sirijovski, Nils Stein, Bruno Studer, Sirja Viitala, Shauna Vronces, Sean Walkowiak, Penghao Wang, Amanda J. Waters, Charlene P. Wight, Weikai Yan, Eric Yao, Xiao-Qi Zhang, Gaofeng Zhou, Zhou Zhou, Nicholas A. Tinker, Jason D. Fiedler, Chengdao Li, Peter J. Maughan, Manuel Spannagl, Martin Mascher

Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09676-7A pangenome of oat, assembled from 33 wild and domesticated oat lines, sheds light on the evolution and genetic diversity of this cereal crop and will aid genomics-assisted breeding to improve productivity and (...)

Nature

Ocean warming threatens the viability of 60% of Antarctic ice shelves

mercredi 29 octobre 2025 par C. Burgard, N. C. Jourdain, C. Mosbeux, J. Caillet, P. Mathiot, C. Kittel

Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09657-wThe viability of Antarctic ice shelves under low rates and high rates of global warming is modelled to estimate when it will become unfeasible for the ice shelves to maintain their present-day (...)

Nature

Plug-in strategy for resistance engineering inspired by potato NLRome

mercredi 29 octobre 2025 par Luyao Wang, Hongbo Li, Yuhang Ke, Ping Zhu, Yuying Li, Pei Wang, Haohao Liu, Yajie Li, Jingqi Chen, Shaoqun Zhou, Li Wan, Savithramma P. Dinesh-Kumar, Suomeng Dong, Sanwen Huang

Nature, Published online: 29 October 2025; doi:10.1038/s41586-025-09678-5A catalogue of nucleotide-binding leucine-rich repeat (NLR) genes in wild and cultivated potato genomes enables the identification of genes that confer protection against late blight, and provides a transgene-free strategy (...)

Nature