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Gene regulatory landscape dissected by single-cell four-omics sequencing

mercredi 1er avril 2026 par Yujie Chen, Zhiyuan Liu, Heming Xu, Jiayu Liu, Mengxuan Wang, Yi Chi, Boyuan Liang, Menghan Liu, Yongli Peng, Hao Ge, Dong Xing

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10322-zCombining single-cell parallel profiling of genome conformation, histone modifications, chromatin accessibility and gene expression reveals dynamics and intranuclear spatial clustering of epigenome profiles, enabling (...)

Nature

The 1000 Chinese Pangenome empowers medical and population genetics

mercredi 1er avril 2026 par Yifei Wang, Zhongqu Duan, Dan Chen, Dandan Shi, Yi Ding, Zhibin Wang, Baoqing Li, Zhiyi Wang, Minmin Guo, Wen Yang, Junren Hou, Wenhao Chen, Yazhou Guo, Wenjie Wei, Yujie Cao, Xiwei Sun, Weiyang Bai, Mingdong Lu, Ting Qi, Xian Shen, Jian Yang

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10315-yDevelopment of the pangenome-informed genome assembly (PIGA) workflow enabled the generation of 1,116 diploid genome assemblies (55 de novo and 1,061 pangenome-informed), representing an extensive resource of medically (...)

Nature

Entanglement and electronic coherence in attosecond molecular photoionization

mercredi 1er avril 2026 par L.-M. Koll, A. J. Suñer-Rubio, T. Witting, R. Y. Bello, A. Palacios, F. Martín, M. J. J. Vrakking

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10230-2Dissociative ionization of H2 molecules by the combination of a phase-locked attosecond laser pair and a few-cycle NIR laser shows that ion–photoelectron entanglement influences electronic coherence in H2+, allowing control (...)

Nature

DNA damage burden causes selective CUX2 neuron loss in neuroinflammation

mercredi 1er avril 2026 par Laura Morcom, Wenlong Xia, Zhaoyang Xu, Yashika Awasthi, Celine Geywitz, Matthew O. Ellis, Tomas Noli, Amel Zulji, Daniel Yamamoto, Gemma C. Girdler, Li Kai, Keying Zhu, Mingming Wei, Xiao-Yan Tang, Kimberly K. Hoi, Julio Gonzalez-Maya, Greg J. Duncan, Adrien M. Vaquie, Diana Gold Diaz, Riki Kawaguchi, Erdong Liu, Yu Sun, Denny Yang, Gregory D. Jordan, I-Ling Lu, Staffan Holmqvist, Theresa Bartels, Katherine Ridley, Jennifer Ja-Yoon Choi, Santos J. Franco, Eric J. Huang, Ben Emery, Daniel Geschwind, Lucas Schirmer, Gabriel Balmus, Brian Popko, Stephen P. J. Fancy, David H. Rowitch

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10310-3DNA damage burden and inadequate repair in CUX2+ cortical layer 2/3 excitatory neurons contributes to selective vulnerability in neuroinflammatory injury.

Nature

These advanced solar cells have an antique source: old bullets

mercredi 1er avril 2026

Nature, Published online: 01 April 2026; doi:10.1038/d41586-026-01001-0Lead recycled from centuries-old ammunition provides raw materials for perovskite solar cells.

Nature

These scientists chased a jet to learn more about ‘lean-burn’ contrails

mercredi 1er avril 2026 par Benjamin Thompson, Shamini Bundell

Nature, Published online: 01 April 2026; doi:10.1038/d41586-026-01052-3In-flight experiment suggests lowering soot emissions might not reduce contrail formation — plus, what can be learnt from fakery in science.

Nature

Structural modifications in strain-engineered bilayer nickelate thin films

mercredi 1er avril 2026 par Lopa Bhatt, Edgar Abarca Morales, Abigail Y. Jiang, Eun Kyo Ko, Yi-Feng Zhao, Noah Schnitzer, Grace A. Pan, Dan Ferenc Segedin, Yidi Liu, Yijun Yu, Charles M. Brooks, Antia S. Botana, Harold Y. Hwang, Julia A. Mundy, David A. Muller, Berit H. Goodge

Nature, Published online: 01 April 2026; doi:10.1038/s41586-026-10446-2Structural modifications in strain-engineered bilayer nickelate thin films

Nature

Daily briefing: The countdown to NASA’s Artemis II Moon mission launch

mercredi 1er avril 2026 par Flora Graham

Nature, Published online: 01 April 2026; doi:10.1038/d41586-026-01097-4The science that NASA’s latest Moon mission will conduct, and why some researchers aren’t fussed about it. Plus, the status of the bird flu outbreak in US cows and what publishers can do about hallucinated citations in (...)

Nature

Structure of the mouse cytoplasmic lattice

mardi 31 mars 2026 par Pengliang Chi, Xiang Wang, Jialu Li, Jingrui Huang, Sicheng Ju, Sibei Liu, Li Yan, Yuechao Lu, Zihan Zhang, Zhuo Han, Jinhong Li, Qianqian Qi, Qingting Liu, Yiren Zeng, Li Guo, Xiaofeng Zhang, Long Gui, Dong Deng

Nature, Published online: 31 March 2026; doi:10.1038/s41586-026-10442-6Structure of the mouse cytoplasmic lattice

Nature

Bunny or bug?

mardi 31 mars 2026

Nature, Published online: 31 March 2026; doi:10.1038/d41586-026-00912-2A curious species of rabbit is detected in the lab, and bullfinches learn the art of primrose eating, in this week’s pick from the Nature archive.

Nature