Sur le Web

Nouveautés sur le Web

Articles les plus récents

Small-molecule modulation of ?-arrestins

mercredi 24 juin 2026 par Alem W. Kahsai, Natalia Pakharukova, Henry Y. Kwon, Kunal S. Shah, Caroline T. del Real, Bowie N. Shreiber, Jason G. Liang-Lin, Paul J. Shim, Mason A. Lee, Van A. Ngo, Allison M. Schwalb, Uyen Pham, Anand Chundi, Haoran Jiang, Emmanuel Flores-Espinoza, Samuel Liu, Preston C. Nibley, Dana K. Bassford, Hyunggu Hahn, Cal A. Kunzle, Brittany N. Thomas, Jihee Kim, Yang Zhou, Jialu Wang, Xingdong Zhang, Jeffrey S. Smith, Lindsay A. M. Rein, Alex R. B. Thomsen, Sudha K. Shenoy, Sudarshan Rajagopal, Lei Shi, Seungkirl Ahn, Howard A. Rockman, Ali Masoudi, Robert J. Lefkowitz

Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10683-5Integrated pharmacological, biochemical, biophysical and structural analyses of small-molecule β-arrestin inhibitors show how they block β-arrestin engagement with activated GPCRs, revealing their mechanism of action and (...)

Nature

Global high-resolution mapping of seagrass to support conservation

mercredi 24 juin 2026 par Jianghai Peng, Jiwei Li, Johannes R. Krause, Mitchell B. Lyons, Nicholas J. Murray, Steven R. Schill, Chris M. Roelfsema, Gregory P. Asner

Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10704-3Global high-resolution mapping shows widespread seagrass loss and degradation since 2019, with most meadows outside protected areas, highlighting urgent conservation and climate-policy (...)

Nature

Disparate privacy risks from medical AI

mercredi 24 juin 2026 par Moritz A. Knolle, Martin J. Menten, Friederike Jungmann, Felix Meissen, Ben Glocker, Daniel Rueckert, Georgios Kaissis

Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10688-0AI models for medical diagnostics are vulnerable to membership inference attacks.

Nature

Dietary cholesterol activates a Ral-dependent pathway driving LDLR turnover

mercredi 24 juin 2026 par Xue Feng, Shuo Zhang, Yuqi Wang, Twisha Kurlagunda, Allyssa Sit, Priyadarshini Jaishankar, Pusu Yang, Sadatsugu Sakane, Se Yong Park, Churaibhon Wisessaowapak, Kaylee Nguyen, Jamie Yan, Himani Pothulu, Catherine Dinh, Felicia Chu, Yuyao Ren, Bichen Zhang, Patrick Secrest, Linmeng Han, Chao-Wei Hung, Preethi Veeragandham, Yuliya Skorobogatko, Tatiana Kisseleva, Philip L.S.M. Gordts, Adam R. Renslo, Peng Zhao, Amit R. Majithia, Alan R. Saltiel

Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10697-zChronic dietary cholesterol activates Ral GTPases, which promote LDLR internalization and lysosomal degradation through RalBP1–REPS1 and CTSA, thereby reducing cholesterol clearance, whereas CTSA inhibition restores LDLR (...)

Nature

Genetic technologies to enhance crop nutritional value under climate change

mercredi 24 juin 2026 par Dominique Van Der Straeten, Mustafa Bulut, Da Cao, Asaph Aharoni, Howarth Bouis, Antonio Granell, Wilhelm Gruissem, Birger Lindberg Møller, Cathie Martin, Holger Puchta, Nese Sreenivasulu, Alain Tissier, Leena Tripathi, Marc Van Montagu, Alisdair R. Fernie

Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10593-6This Review reflects on the joint power of genetic technologies, including untapped CRISPR–Cas techniques to combat hidden hunger and improve crop resilience, and argues in favour of their combined use to overcome these (...)

Nature

The mutational landscape of STING-induced immunity

mercredi 24 juin 2026 par Bing Zhang, Pengbiao Xu, Yu Meng, Laure Gallay, François Lestelle, Hélène Morel, Marie-Louise Frémond, Bruno E. Correia, Andrea Ablasser

Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10685-3A massively parallel assay systematically charts the sequence-function landscape of the STING signalling protein, and the findings define molecular principles that tune STING activity and show its functional potential across (...)

Nature

AI tool spots antibiotics that fight drug-resistant gonorrhoea

mercredi 24 juin 2026

Nature, Published online: 24 June 2026; doi:10.1038/d41586-026-01987-7The bacterium Neisseria gonorrhoeae has evolved resistance to most antibiotics used to treat it, but a machine-learning screen reveals potential therapies.

Nature

Volcanic magma sculpts eerie domes on the sea floor

mercredi 24 juin 2026

Nature, Published online: 24 June 2026; doi:10.1038/d41586-026-01986-8Carbon dioxide bubbling up from underground material can solidify into formations of up to five metres tall.

Nature

On the robustness of topological gap detection via transport

mercredi 24 juin 2026 par Henry F. Legg

Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10567-8On the robustness of topological gap detection via transport

Nature

Medical records could be revealed by AI training-data vulnerability

mercredi 24 juin 2026 par Benjamin Thompson, Nick Petri? Howe

Nature, Published online: 24 June 2026; doi:10.1038/d41586-026-02032-3Identification risks are more severe for underrepresented groups in the training data — plus, evidence that the Universe is more uneven than assumed.

Nature