Sur le Web

Nouveautés sur le Web

Articles les plus récents

Spatial atlas of diabetic kidney disease reveals a B cell-rich subgroup

mercredi 29 avril 2026 par Bernhard Dumoulin, Jonathan Levinsohn, Konstantin A. Klötzer, Chenyu Li, Liran Mao, Eunji Ha, Samer Mohandes, Thao Nguyen, Luca Paruzzo, Daigoro Hirohama, Victoria Fang, Vijay G. Bhoj, Hamideh Parhiz, Magaiver Andrade-Silva, Amin Abedini, Andi Bergeson, Daniel Traum, Michael J. May, Klaus H. Kaestner, Marco Ruella, Fiona Elizabeth McAllister, A. Ari Hakimi, Mingyao Li, Matthew Palmer, E. John Wherry, Christopher A. Hunter, Michael Paul Cancro, Raymond Townsend, Gaia Coppock, Manisha Singh, Michael Ross, James Tumlin, Kirk Campbell, Amy Mottl, Christos Argyropoulos, Tamara Isakova, Salem Almaani, Rupali Avasare, Richard Lafayette, Julia Scialla, Randy Luciano, Shweta Bansal, Frank Brosius, Ankit Mehta, Oliver Lenz, Nelson Kopyt, Piettro Canetta, Matthias Kretzler, Jeffrey Schelling, Alexis Hofherr, Steven S. Pullen, Andrew Thorley, Ching Shang, Erding Hu, Anil Karihaloo, Kishor Devalaraja-Narashimha, Katalin Susztak

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10363-4A single-cell spatial atlas identifies a B cell-predominant microenvironment within the profibrotic tubular niche that marks a subset of patients with diabetic kidney disease with rapid (...)

Nature

Translation-dependent degradation of cas12 mRNA triggered by an anti-CRISPR

mercredi 29 avril 2026 par Nicole D. Marino, Alexander Talaie, Milan Gerovac, Jorge L. Rodriguez, Andrew D. Schmidt, Theresa J. Astmann, Héloïse Carion, Anya Flood Taylor, Jessica Liliedahl, Surabhi Haniyur, Kristi Zoga, Matthew C. Johnson, Leandro Buhlmann, Kuei-Ho Chen, Sukrit Silas, Yuping Li, Yang Zhang, Danielle L. Swaney, Jörg Vogel, Joseph Bondy-Denomy

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10440-8The anti-CRISPR protein AcrVA2 specifically interrupts Cas12a biogenesis by triggering co-translational mRNA degradation.

Nature

Vaccination generates broadly cross-neutralizing antibodies to the HIV Env apex

mercredi 29 avril 2026 par Javier Guenaga, Monika Ádori, Shridhar Bale, Swastik Phulera, Ioannis Zygouras, Fabian-Alexander Schleich, Xaquin Castro Dopico, Sashank Agrawal, Miyo Ota, Richard Wilson, Jocelyn Cluff, Tamar Dzvelaia, Marco Mandolesi, Wen-Hsin Lee, Agnes A. Walsh, Mariane B. Melo, Laurent Verkoczy, Darrell J. Irvine, Martin Corcoran, Ian A. Wilson, Diane Carnathan, Guido Silvestri, Andrew B. Ward, Gabriel Ozorowski, Gunilla B. Karlsson Hedestam, Richard T. Wyatt

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10429-3A vaccination strategy using heterologous HIV Env trimers covalently coupled to liposomes for multivalent display generates cross-neutralizing HIV serum antibody responses in non-human primates, mimicking infection-elicited (...)

Nature

Transdimensional anomalous Hall effect in rhombohedral thin graphite

mercredi 29 avril 2026 par Qingxin Li, Hua Fan, Min Li, Yinghai Xu, Junwei Song, Anqi Wang, Kenji Watanabe, Takashi Taniguchi, Jing-Jing Chen, Zhenbing Tan, Jie Shen, Hua Jiang, James C. Hone, Cory R. Dean, Kostya S. Novoselov, Xin-Cheng Xie, Geliang Yu, Yue Zhao, Jianpeng Liu, Lei Wang

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10471-1The experimental observation of a fundamentally new type of anomalous Hall effect that couples both in-plane and out-of-plane orbital magnetizations in multilayer rhombohedral graphene is (...)

Nature

Improving access to essential medicines via decision-aware machine learning

mercredi 29 avril 2026 par Angel Tsai-Hsuan Chung, Jatu Abdulai, Patrick Bayoh, Lawrence Sandi, Francis Smart, Hamsa Bastani, Osbert Bastani

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10433-7Nationwide deployment of a novel decision-aware machine learning framework as a decision support tool for the allocation of essential medicines in Sierra Leone resulted in improved access to essential healthcare in this (...)

Nature

Digital quantum magnetism on a trapped-ion quantum computer

mercredi 29 avril 2026 par R. Haghshenas, E. Chertkov, M. Mills, W. Kadow, S.-H. Lin, Y. H. Chen, C. Cade, I. Niesen, T. Beguši?, M. S. Rudolph, C. Cirstoiu, K. Hémery, C. Mc Keever, M. Lubasch, E. Granet, C. H. Baldwin, J. P. Bartolotta, M. Bohn, J. J. Burau, J. Cline, M. DeCross, J. M. Dreiling, C. Foltz, D. Francois, J. P. Gaebler, C. N. Gilbreth, J. Gray, D. Gresh, A. Hall, A. Hankin, A. Hansen, N. Hewitt, C. A. Holliman, R. B. Hutson, M. Iqbal, N. Kotibhaskar, E. Lehman, D. Lucchetti, I. S. Madjarov, K. Mayer, A. R. Milne, S. A. Moses, B. Neyenhuis, G. Park, A. R. Perry, B. Ponsioen, M. Schecter, P. E. Siegfried, D. T. Stephen, B. G. Tiemann, M. D. Urmey, J. Walker, A. C. Potter, D. Hayes, G. K.-L. Chan, F. Pollmann, M. Knap, H. Dreyer, M. Foss-Feig

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10445-3Simulations performed using Quantinuum’s H2 trapped-ion quantum computer for observing thermalization on challenging timescales demonstrate the usefulness of digital quantum computers for investigating continuous-time (...)

Nature

Safety and efficacy of intratumoural anti-CTLA4 with intravenous anti-PD1

mercredi 29 avril 2026 par Lambros Tselikas, Sandrine Susini, Matthieu Texier, Andrey Yurchenko, Emilie Routier, Mona Amini-Adle, Edi Tihic, Séverine Mouraud, François-Xavier Danlos, Samy Ammari, Thibault Raoult, Séverine Roy, Delphine Bredel, Siham Farhane, Lydie Cassard, Irma Molinaro, Alexander Eggermont, Jean-Charles Soria, Laurence Zitvogel, Christophe Massard, Angelo Paci, Thierry de Baere, Jean-Yves Scoazec, Nathalie Chaput, Sergey Nikolaev, Nicolas Meyer, Céleste Lebbé, Stéphane Dalle, Caroline Robert, Aurélien Marabelle

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10341-wThe phase 1b NIVIPIT trial shows that in combined therapy with intravenous nivolumab (anti-PD1), intratumoural administration of ipilimumab (anti-CTLA4) offers improved safety and greater efficacy compared with intravenous (...)

Nature

Recycling of spin-triplet excitons in organic photovoltaics

mercredi 29 avril 2026 par Qian Li, Lingchen Kong, Le Mei, Shanchao Ouyang, Yiwen Ji, Baobing Fan, Huanhuan Gao, Wei Gao, Feng Qi, Zhiqiang Guan, Nan Zhang, Hin-Lap Yip, Chun-Sing Lee, Dangyuan Lei, Chunfeng Zhang, Sai-Wing Tsang, Xian-Kai Chen, Francis R. Lin, Alex K.-Y. Jen

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10419-5Triplet excitons in OPVs can redissociate via the charge-transfer state into free carriers, reducing losses and improving efficiency, enabled by molecular design controlling singlet–triplet energetics through exciton (...)

Nature

Decarboxylative alkylation of alkenes

mercredi 29 avril 2026 par Triptesh Kumar Roy, Federico Maria Tamborini, Roland Petzold, Jianhan Fu, Yiben Tang, Tobias Ritter

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10463-1A Pd-catalysed method enables regio- and diastereoselective C–H alkylation of diverse alkenes using carboxylic acids, expanding synthetic access to complex substituted (...)

Nature

Immunity gets a boost from a surprising place — breakfast

mercredi 29 avril 2026 par Nick Petri? Howe, Maren Hunsberger

Nature, Published online: 29 April 2026; doi:10.1038/d41586-026-01406-xEating a meal could lead to T cells springing into action more quickly— plus, 40 years after Chornobyl, how future nuclear calamities can be avoided.

Nature