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Roman Empire’s collapse created a genetic melting pot in Europe

mercredi 29 avril 2026 par Ewen Callaway

Nature, Published online: 29 April 2026; doi:10.1038/d41586-026-01395-xGenome evidence points to a slow blending of peoples — not a violent tide of invaders — that laid the foundations of modern Europe’s diverse ancestry.

Nature

Daily briefing: Octopuses’ strange brains might teach us what intelligence really is

mercredi 29 avril 2026 par Flora Graham

Nature, Published online: 29 April 2026; doi:10.1038/d41586-026-01431-wCephalopods are very smart, but have brains that evolved very differently than vertebrates. Plus, detailed maps of olfactory receptors in mice transform what we know about (...)

Nature

Engineered blood clots stop bleeding in seconds

mercredi 29 avril 2026 par Malcolm Xing, Gaoxing Luo

Nature, Published online: 29 April 2026; doi:10.1038/d41586-026-01150-2Red blood cells have been modified to form strong clots that halt any bleeding almost instantly and then promote tissue regeneration.

Nature

Submicrometre sampling of living cells by macrophages

mercredi 29 avril 2026 par Amy C. Fan, Rukman R. Thota, Nina Serwas, Vivasvan S. Vykunta, Kyle Marchuk, Megan K. Ruhland, Lauren Liu, Grace Johnson, Austin Edwards, Matthew F. Krummel

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10435-5Macrophages can sample antigens from living cells through a trogocytosis-like mechanism that routes ingested material away from degradation, a finding that delineates a previously unknown pathway for antigen presentation to (...)

Nature

Racial diversity in higher education is associated with higher student salaries

mercredi 29 avril 2026 par Debanjan Mitra, Peter N. Golder, Mariya Topchy

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10425-7A longitudinal study shows that racial diversity in higher education is associated with higher student salaries at graduation, indicating that policies to increase or leverage racial diversity enhance human capital and (...)

Nature

Evolutionary characterization of lung cancer metastasis

mercredi 29 avril 2026 par Sonya Hessey, Abigail Bunkum, Ariana Huebner, Kerstin Haase, Kristiana Grigoriadis, Cristina Naceur-Lombardelli, Wing Kin Liu, Caitlin F. Harrigan, Charlotte Grieco, Daniele Marinelli, Boyue Ding, Carlos Martínez-Ruiz, Piotr Pawlik, Mark S. Hill, Olivia Lucas, Corentin Richard, Oriol Pich, Kerstin Thol, Takahiro Karasaki, Sophia Ward, Foteini Athanasopoulou, Monica Sivakumar, Selvaraju Veeriah, Antonia Toncheva, Andrew J. Rowan, Paulina Prymas, Hayley Bridger, Miriam Mitchison, Elaine Borg, Mary Falzon, Ian Proctor, Ula Mahadeva, Anna Green, Martin D. Forster, Sarah Benafif, Tanya Ahmad, Siow Ming Lee, Dionysis Papadatos-Pastos, Babu Naidu, Gerald Langman, Matthew G. Krebs, Pedro Oliveira, Fiona H. Blackhall, Yvonne Summers, Jamie Weaver, John Le Quesne, Anne Thomas, Cathy Richards, Dean A. Fennell, Sanjay Jogai, Judith Cave, Patricia Roxburgh, Sioban Fraser, Alan Kirk, Kevin G. Blyth, Peter Russell, Crispin T. Hiley, Allan Hackshaw, Jason F. Lester, Amrita Bajaj, Apostolos Nakas, Azmina Sodha-Ramdeen, Claire Wilson, Molly Scotland, Rebecca Boyles, Sean Dulloo, Sridhar Rathinam, Gurdeep Matharu, Jacqui A. Shaw, Ekaterini Boleti, Heather Cheyne, Gillian Price, Keith M. Kerr, Mohammed Khalil, Shirley Richardson, Tracey Cruickshank, Jack French, Kayleigh Gilbert, Akshay J. Patel, Aya Osman, Gary Middleton, Helen Shackleford, Madava Djearaman, Mandeesh Sangha, Angela Leek, Adam Atkin, Anshuman Chaturvedi, Antonio Paiva-Correia, Colin R. Lindsay, Eustace Fontaine, Felice Granato, Jack Davies Hodgkinson, Juliette Novasio, Katherine D. Brown, Kandadai Rammohan, Leena Joseph, Mathew Carter, Nicola Totton, Paul Bishop, Philip A. J. Crosbie, Sara Waplington, Jonathan Tugwood, Caroline Dive, Hugo JWL Aerts, Gareth A. Wilson, Aino-Maija Leppä, Alexander A. Azizi, Lydia Y. Liu, Jonas Demeulemeester, Miklos Diossy, Nicolai J. Birkbak, Peter Van Loo, Rachel Rosenthal, Roberto Salgado, Roland F. Schwarz, Tom L. Kaufmann, Zoltan Szallasi, Alexander M. Frankell, Angela Dwornik, Angeliki Karamani, Karen Grimes, Benny Chain, Carla Castignani, Chris Bailey, Cian Murphy, Clare E. Weeden, Clare Puttick, David R. Pearce, Despoina Karagianni, Dimitria Brempou, Emilia L. Lim, Emma C. Colliver, Emma Hazelwood, Emma Nye, Erik Sahai, Eva Grönroos, Francisco Gimeno-Valiente, Gemma Foulds, George Kassiotis, Georgia Moth, Georgia Stavrou, Helen L. Lowe, Ieva Usaite, Iva Mladenova, Jacki Goldman, James L. Reading, James R. M. Black, Jayant K. Rane, Jeanette Kittel, John A. Hartley, Jorge Martin Arana, Karl S. Peggs, Katey S. S. Enfield, Katherine Honan, Kayalvizhi Selvaraju, Kexin Koh, Krupa Thakkar, Leah Ensell, Lucrezia Patruno, Maise Al Bakir, Mansi Shah, Maria Litovchenko, Maria Zagorulya, Michalina Magala, Michelle M. Leung, Mickael Escudero, Mihaela Angelova, Nnennaya Kanu, Oliver Shutkever, Philip Hobson, Richard Kevin Stone, Rija Zaidi, Robert Bentham, Robert Goldstone, Roberto Vendramin, Sadegh Saghafinia, Samuel Gamble, Seng Kuong Anakin Ung, Sergio A. Quezada, Sharon Vanloo, Sian Harries, Stefan Boeing, Stephan Beck, Supreet Kaur Bola, Teresa Marafioti, Theepan Visakan, Thomas B. K. Watkins, Thomas Patrick Jones, Victoria Spanswick, Vittorio Barbè, Wei-Ting Lu, William Hill, Woody Z. Zhang, Yin Wu, Yutaka Naito, Zoe Ramsden, Catarina Veiga, Charles-Antoine Collins-Fekete, Francesco Fraioli, Gary Royle, Paul Ashford, Alexander James Procter, Arjun Nair, Asia Ahmed, David Lawrence, Davide Patrini, Emilie Martinoni Hoogenboom, Fleur Monk, James W. Holding, Junaid Choudhary, Kunal Bhakhri, Magali N. Taylor, Maria Chiara Pisciella, Neal Navani, Pat Gorman, Reena Khiroya, Ricky M. Thakrar, Robert CM Stephens, Sam M. Janes, Steve Bandula, Zoltan Kaplar, Aoife Walker, Camilla Pilotti, Rachel Leslie, Salomey Kellett, Anca Grapa, Hanyun Zhang, Khalid AbdulJabbar, Xiaoxi Pan, Yinyin Yuan, David Chuter, Mairead MacKenzie, Aiman Alzetani, Patricia Georg, Serena Chee, Eric Lim, Alexandra Rice, Anand Devaraj, Andrew G. Nicholson, Chiara Proli, Daniel Kaniu, Harshil Bhayani, Hema Chavan, Hilgardt Raubenheimer, Lyn Ambrose, Mpho Malima, Nadia Fernandes, Paulo De Sousa, Pratibha Shah, Sarah Booth, Silviu I. Buderi, Simon Jordan, Sofina Begum, Madeleine Hewish, Sarah Danson, Michael J. Shackcloth, Lily Robinson, Andrew Kidd, Craig Dick, Jennifer Whiteley, Mathew Thomas, Mohammed Asif, Nikos Kostoulas, Rocco Bilancia, Zainab Kalokoh, Elizabeth Keene, Theepan Vikasan, Karen Ambrose, Mike Gavrielides, Nitzan Rosenfeld, Amrit Roshan, Cecilie Agergaard Soerensen, Ben Solomon, Lavinia Tan, Ana Parreira, Corinne Faivre-Finn, Fabio Gomes, Igor Gomez-Randulfe, Jack Webster, Laura Cove-Smith, Pamela Maroa, Paul Taylor, Raffaele Califano, Sara Tenconi, Adam Peryt, Aman Coonar, Amanda Stone, Caroline Sanganee, Martin Goddard, Stephen Preston, Giuseppe Aresu, Jane Lichfield, Julia Knight, Lauren DSA, Maria Manuela Urda, Maria Nizami, Robert Rintoul, Zoe Armstrong, Abiya Mathew, Damalie Namwanja, Nicky Thomson, Philip Earwaker, Kai-Keen Shiu, John Bridgewater, Daniel Hochhauser, Tariq Enver, Ron Sinclair, Zoe Rhodes, Mark Linch, Sebastian Brandner, Heather Shaw, Gerhardt Attard, Faye Gishen, Francisco Gimeno Valiente, Adrienne Flanagan, Osvaldas Vainauskas, Anna Wingate, Daniel Wetterskog, A. M. Mahedi Hasan, Stefano Lise, Gianmarco Leone, Anuradha Jayaram, Constantine Alifrangis, Ursula McGovern, Kerry Bowles, Athanasia Vargiamiou, Christopher Aled Chamberlain, Welles Robinson, Iain McNeish, Nataly Ojeda Mosquera, Jiali Liu, Felix O’Farrell, Chenelle Marcel, Samra Turajlic, James Larkin, Lisa Pickering, Andrew Furness, Kate Young, Will Drake, Kim Edmonds, Nikki Hunter, Mary Mangwende, Lauren Grostate, Lavinia Spain, Scott Shepherd, Haixi Yan, Benjamin Shum, Zayd Tippu, Brian Hanley, Charlotte Spencer, Max Emmerich, Camille Gerard, Eleanor Carlyle, Steve Hazell, Hardeep Mudhar, Christina Messiou, Arash Latifoltojar, Annika Fendler, Fiona Byrne, Husayn Pallikonda, Irene Lobon, Alexander Coulton, Anne-Laure Cattin, Daqi Deng, Hugang Feng, Nadia Yousaf, Sanjay Popat, Charlotte Milner-Watts, Aida Murra, Justine Korteweg, Lauren Terry, Jennifer Biano, Kema Peat, Emma Turay, Peter Hill, Marija Miletic, Anadil Javaid, Jennifer Thomas, Bakir Kudic, Orla McGowan, Dharmista Ramesh, Oznur Saka, Sinem Arslan, Laura Marandino, Reina Ammar, Gurneet Kapur, Dilruba Kabir, David McMahon, Alexius John, Foteini Kalofonou, Debra Josephs, Sheeba Irshad, James Spicer, Ruby Stewart, Natasha Wright, Ruxandra Mitu, Deborah Enting, Sarah Rudman, Sharmistha Ghosh, Eleni Lena Karapanagiotou, Elias Pintus, Andrew Tutt, James D. Brenton, Nicola Thompson, Rebecca Fitzgerald, Merche Jimenez-Linan, Elena Provenzano, Anna Paterson, Kieren Allinson, Grant D. Stewart, Ultan McDermott, Tim Maughan, Olaf Ansorge, Peter Campbell, Mat Carter, Charlotte Poile, Kudazyi H. Kutywayo, Maurice R. Dungey, Jens Claus Hahne, Shobhit Baijal, Charlotte Ferris, Hollie Bancroft, Amy Kerr, Joanne Webb, Salma Kadiri, Bernard Olisemeke, Rodelaine Wilson, Ian Tomlinson, Luke Nolan, Samantha Holden, Tania Fernandes, Mairead McKenzie, Shivani Patel, David A. Moore, Simone Zaccaria, Nicholas McGranahan, Charles Swanton, Mariam Jamal-Hanjani

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10428-4DNA-sequencing data from primary tumours and paired metastases from participants in the TRACERx lung study and PEACE autopsy programme are used to analyse the metastatic diversity of advanced non-small cell lung cancer and (...)

Nature

Postprandial lipid metabolism durably enhances T cell immunity

mercredi 29 avril 2026 par Alok Kumar, Dayana B. Rivadeneira, Isha Mehta, Bingxian Xie, Rachel Cumberland, Supriya K. Joshi, Jitendra S. Kanshana, William G. Gunn, Victoria Dean, Angelina Parise, Kristin Morder, Erica S. Myers, Steven J. Mullett, Richard T. Cattley, Stacy L. Gelhaus, Abigail E. Overacre-Delgoffe, Jishnu Das, William F. Hawse, Alison B. Kohan, Greg M. Delgoffe

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10432-8Experiments in mice and humans show enhancement of T cell function following fasting and refeeding, caused by persistent immunometabolic reprogramming, with potential implications for nutritional interventions and adoptive (...)

Nature

Intrinsic polar vortex crystals in A-site layer-ordered perovskites

mercredi 29 avril 2026 par Chao Xu, Nengneng Luo, Junyi Yue, Changsheng Chen, Tieyuan Bian, Chi Zhang, Xiangli Che, Jianwen Liang, Molly Meng-Jung Li, Jun Yin, Zhen Chen, Shujun Zhang, Xiaoqing Pan, Ye Zhu

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10470-2A two-dimensional polar hedgehog lattice spontaneously forms in layer-ordered perovskites, showing stable topological ferroelectric states without external constraints and enabling new pathways for functional material (...)

Nature

Demography and life histories across the Roman frontier in Germany 400–700 ce

mercredi 29 avril 2026 par Jens Blöcher, Leonardo Vallini, Maren Velte, Raphael Eckel, Léa Guyon, Laura Winkelbach, Mark G. Thomas, Nadia Gharehbaghi, Cassandra T. Mitchell, Jonas Schümann, Sophie Köhler, Elsa Seyr, Katharina Krichel, Sophie Rau, Jana Hirsch, Jana Duras, Paul Cloarec-Pioffet, Andreas Füglistaler, Kristin Klement, Miriam Wilkenhöner, Lisa Vetterdietz, Francesca Gentilin, Melany Müller, Anna-Lena Mücke, Nicoletta Zedda, Youssef Tawfik, Eveline Saal, George McGlynn, Barbara Bramanti, Jörg Orschiedt, Regina Molitor, Barbara Fliß, Ines Spazier, David Shankland, Claus Vetterling, Kurt Karpf, Vera Planert, Stefan Hölzl, Silvia Codreanu-Windauer, Dieter Quast, Ilija Miki?, Sven Fiedler, Bernd Päffgen, Maxime Brami, Thomas Richter, Raphaëlle Chaix, Susanne Brather-Walter, Peter Steffens, Markus Marquart, Thomas Becker, Jochen Haberstroh, Mischa Meier, Sebastian Schmidt-Hofner, Sebastian Brather, Michaela Harbeck, Steffen Patzold, Daniel Wegmann, Joachim Burger

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10437-3Analysis of 258 ancient genomes from southern Germany reveals a major demographic shift during the late fifth century, yet family structures persisted from Late Roman times, demonstrating cultural continuity despite profound (...)

Nature

Pervasive and programmed nucleosome distortion on single chromatin fibres

mercredi 29 avril 2026 par Marty G. Yang, Hannah J. Richter, Simai Wang, Colin P. McNally, Camille M. Moore, Ali Emadi, Nicole E. Harris, Simaron Dhillon, Michela Maresca, Huimin Pan, Hayden Saunders, Ruiqiao Yang, Megan S. Ostrowski, Erika C. Anderson, Elzo de Wit, Jacquelyn J. Maher, Yuhong Fan, Geeta J. Narlikar, Elphège P. Nora, Holger Willenbring, Hani Goodarzi, Vijay Ramani

Nature, Published online: 29 April 2026; doi:10.1038/s41586-026-10418-6An analytical pipeline called Iteratively Defined Lengths of Inaccessibility (IDLI) maps the genome-wide occupancy of a range of nucleosome types and shows that most nucleosomes exhibit programmed ‘distortion’, in which the (...)

Nature