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Moderate volcanic eruptions and extreme wildfires humidify the stratosphere

mercredi 1er juillet 2026 par Yifeng Peng, William Randel, Owen Brian Toon, Xinyue Wang, Kai Qie, Sean M. Davis, Karen H. Rosenlof, Pengfei Yu

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10731-0Observations and modelling show that volcanic eruptions and extreme wildfires have systematically increased stratospheric water vapour since 2005, revealing that these episodic aerosol perturbations are a previously (...)

Nature

Casdatifan shows durable response linked to HIF-2? biology in kidney cancer

mercredi 1er juillet 2026 par Toni K. Choueiri, Jamie Merchan, Amita Patnaik, Alexandra Drakaki, Brian I. Rini, Sun Young Rha, Jae Lyun Lee, Moshe C. Ornstein, Rohit Kumar, Clara Hwang, Yusra Shao, Se Hoon Park, Pedro C. Barata, Bradley A. McGregor, Paul Foster, Jianfen Chen, Melissa Eisen, Hunter Cole, Ben Weeder, Yinghui Guan, Jaskirat Singh, Angelo Kaplan, Soonweng Cho, Richard Markus, Omar Kabbarah, Rana R. McKay

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10718-xMonotherapy with the HIF-2α inhibitor casdatifan achieves meaningful, durable responses linked to HIF-2α biology with manageable safety in the treatment of individuals with clear cell renal cell (...)

Nature

Competing programs shape cortical sensorimotor–association axis development

mercredi 1er juillet 2026 par Jeremiah Tsyporin, Menglei Zhang, Cai Qi, Ashlea Segal, Xinyun Li, Hyojin Kim, Sang-Hun Choi, Ivan Pavlovic, Sara Bandiera, Thomas Finn, Suel-Kee Kim, Akemi Shibata, Takumi Nakamura, Kohei Onishi, Ziqin Zhang, Elijah Hammarlund, Graham Su, Nikkita Salla, Joy Kachko, Christi Hawley, Shuiyu Li, Daniel Z. Doyle, Xueyan Peng, Timothy Nottoli, Nuria Ruiz-Reig, Fadel Tissir, Yasushi Nakagawa, Erica Herzog, Shaojie Ma, Kevin Gobeske, Kartik Pattabiraman, Tomomi Shimogori, Alvaro Duque, Alex Fornito, Hao Huang, Mikihito Shibata, Bin Chen, Nenad Sestan

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10699-xMultispecies evidence supports the multinodal induction–exclusion in network development model, in which sensorimotor-to-association patterning is governed by competing processes of induction and exclusion driven by two (...)

Nature

Food web complexity underlies biodiversity effects on ecosystem functioning

mercredi 1er juillet 2026 par Andrew D. Barnes, Ulrich Brose, Nico Eisenhauer, Emilio Berti, Mario Brauns, Susan L. Eggert, David Garcia-Callejas, Darren P. Giling, Robert O. Hall Jr., Jes Hines, Malte Jochum, Daniil I. Korobushkin, Susanne Kortsch, Pavel Kratina, Marina Manca, Jordi-René Mor, Marie C. Nordström, Eoin J. O’Gorman, David Ott, Daniel M. Perkins, Benjamin Rosenbaum, Ruslan A. Saifutdinov, Victor S. Saito, Andrew J. Tanentzap, Catarina Vinagre, Benoit Gauzens

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10710-5Analyses of the relationship between taxon richness and multi-trophic ecosystem functioning across marine, lake, stream and soil ecosystems show that food web complexity underlies biodiversity effects on ecosystem (...)

Nature

N⁴-Acetylcytidine enhances synthetic mRNA translation yield and fidelity

mercredi 1er juillet 2026 par Sarah Schiffers, Blake W. Nelson, Maria Prigge, Shriya Krishna, Leslie Watkins, Yining Zhu, Nishu Tyagi, Hamid Beiki, Sudipto Das, Ayush Raman, Jingyao Ma, Thorkell Andresson, Hai-Quan Mao, Bin Wu, Shalini Oberdoerffer

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10729-8Different RNA modifications elicit different translation elongation rates for in vitro transcribed mRNAs that result in disparate translation outputs and fidelity, as shown here for N4-acetylcytidine versus the industry (...)

Nature

Aerosols and hydrocarbons in the atmosphere of a white dwarf planet

mercredi 1er juillet 2026 par Ryan J. MacDonald, Christopher E. O’Connor, Victoria A. Boehm, E. M. May, David K. Sing, Elijah Mullens, L. C. Mayorga, Trevor O. Foote, Simon Blouin, Logan A. Pearce, Nikole K. Lewis, Jeff Valenti, Natasha E. Batalha, Maura Lally, Joshua D. Lothringer, Mark S. Marley, Ishan Mishra, Susan E. Mullally

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10514-7Transmission spectroscopy of the planet WD 1856 b, orbiting a white dwarf, with the James Webb Space Telescope reveals the presence of hydrocarbons and aerosols in its atmosphere, providing insight into its mass and heating (...)

Nature

TROP2 targeting reveals therapy-driven cell state dynamics in colorectal cancer

mercredi 1er juillet 2026 par Nuria Vaquero-Siguero, Nikolaos Georgakopoulos, Maria C. Puschhof, Ioannis Chiotakakos, Jasmin Meier, Sigrid K. Fey, Gabriele Diamante, Manuel Mastel, Aitana Guiseris-Martinez, Guillaume Belthier, Nikolai Schleußner, Julia Volk, Carolin Artmann, Bryce Lim, Ronald Koschny, Cyrill Wehling, Kyanna S. Ouyang, Michael Günther, Solveig Kuss, Paula Hoffmeister, Moritz Mall, Jens Neumann, Steffen Ormanns, Martin Schneider, Thomas Schmidt, Jens Puschhof, Andreas Trumpp, Jacco van Rheenen, Julio Saez-Rodriguez, Bruno C. Köhler, Rene Jackstadt

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10705-2TROP2 marks poor-prognosis colorectal cancer cells with fetal-like, therapy-resistant states, and therapeutic targeting of TROP2 with antibody–drug conjugates in combination with chemotherapy enhances treatment efficacy by (...)

Nature

Heat-triggered phospholipid flipping stabilizes plasma membrane fluidity

mercredi 1er juillet 2026 par Shijun Fan, Peng Gao, Kailai Huang, Wei Ying, Lei Xu, Weilan Chen, Huan Ye, Yi Xi, Yan Yang, Hang Qian, Ting Li, Bin Tu, Hua Yuan, Bingtian Ma, Yuping Wang, Zhaohui Zhong, Jiawei Xiong, Hao Wang, Liangzhu Kang, Shiwen Tang, Xuewei Chen, Linfeng Sun, Chengbin Xiang, Shigui Li, Peng Qin

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10726-xIn rice, the P4-ATPase complex OsALA5–OsALIS2 rapidly stabilizes membrane fluidity in response to high temperature by flipping saturated phosphatidylcholines to the cytosolic leaflet of the plasma (...)

Nature

Directly probing the carrier transfer length in 2D-material transistors

mercredi 1er juillet 2026 par Zi-Liang Yang, Bo-Chao Huang, Yu-Kuan Lin, Yan-Ruei Lin, Hung-Chang Hsu, Hao-Yu Chen, Yi Wan, Kai-Wei Tseng, Shu-Ting Yang, Han-Chieh Lo, You-Jia Huang, Fangyuan Zheng, Ni Yang, Wanqing Meng, Jiacheng Min, Po-Cheng Huang, Yann-Wen Lan, Lain-Jong Li, Ya-Ping Chiu

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10707-0Cross-sectional scanning tunnelling microscopy shows a 2 nm carrier transfer length in bismuth-contacted monolayer MoS2 transistors, defining metal-contact scaling limits for sub-10 nm 2D electronic (...)

Nature

Restoring cortical disinhibition improves Huntington’s disease phenotypes

mercredi 1er juillet 2026 par Sonja Blumenstock, David Arakelyan, Nicholas del Grosso, Sonja Schneider, Yufeng Shao, Enida Gjoni, Rüdiger Klein, Irina Dudanova, Takaki Komiyama

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10671-9In a mouse model of Huntington’s disease, targeted modulation of neuronal activity restores network function and improves motor deficits.

Nature