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Endocannabinoids facilitate reward engagement through retrograde gain control

mercredi 26 août 2026 par David J. Marcus, Anthony E. English, Gunn Chun, Emmaline F. Seth, Rachel Oommen, Sabrina Hwang, Bailey A. Wells, Sean C. Piantadosi, Azra Suko, Sayaka J. Kenmochi, Anupritaa A. Parasnis, Ethan Ancell, Yulong Li, Larry S. Zweifel, Benjamin B. Land, Nephi Stella, Michael R. Bruchas

Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10967-wA key role for retrograde neuromodulatory signalling in motivated behaviour is shown through dynamic endocannabinoid release within a thalamostriatal circuit that regulates behavioural engagement during reward (...)

Nature

Video reconstruction of variable VLBI observations with neural fields

mercredi 26 août 2026 par Marianna Foschi, Brandon Zhao, Antonio Fuentes, Katherine L. Bouman, José L. Gómez, Aviad Levis

Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10988-5The kine neural reconstruction algorithm produces high-resolution, time-continuous very long baseline interferometry videos, enabling direct measurement of instantaneous plasma velocities and detailed kinematic analysis of (...)

Nature

Aberrant excitatory neuronal ERBB4 promotes Alzheimer’s disease pathology

mercredi 26 août 2026 par Se Young Lee, Eunseok Park, Ha-Eun Lee, Seongbin Kim, Yeji Yeo, Juwon Park, Young-Jin Choi, Kiheon Lee, Ki-Jun Yoon, Sanghoon Park, Eunjoon Kim, Jae-Ick Kim, Won-Suk Chung

Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10964-zNeuroinflammation alone may be dispensable for early synapse loss in Alzheimer’s disease.

Nature

Critical zone processes limit alkalinity export from natural basaltic systems

mercredi 26 août 2026 par L. A. Derry, K. Maher, O. A. Chadwick

Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10936-3Observations from natural volcanic watersheds demonstrate attenuation of alkalinity fluxes along the complete reactive pathways from soil to river that lead to reductions in exported alkalinity, indicating the limiting (...)

Nature

A binding-to-release strategy for targeted anticancer drug delivery

mercredi 26 août 2026 par Zihao Wen, Mengxin Xu, Zijun Yan, Ziren Kong, Yupeng Wang, Pei Liu, Junyi Chen, Yanzhao Liu, Xi-Yang Cui, Tianyi Cen, Xinwei Li, Yuedan Zheng, Zichen Gu, Da Xu, Qiang Xu, Yaping Luo, Changlun Wang, Zhibo Liu

Nature, Published online: 26 August 2026; doi:10.1038/s41586-026-10971-0A binding-to-release drug conjugate strategy enables targeted payload release without cellular internalization, improving tumour specificity, efficacy and expanding therapeutic targets beyond conventional drug (...)

Nature

These rodent OnlyFans stars are helping to fund scientific research

mardi 25 août 2026 par Elliot Yates

Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02550-0The platform, mostly known for its adult content, has provided a financial lifeline amid US federal-funding uncertainty. And now the marmots have their own cryptocurrency (...)

Nature

More than 18,000 questionable images found in antibody catalogues of 15 companies

mardi 25 août 2026 par Dan Garisto

Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02635-wScience sleuth’s findings raise questions for researchers working to improve the reliability of commercial antibodies.

Nature

Protecting education in the middle of war zones

mardi 25 août 2026 par Ali F. Meghdari

Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02634-xProtecting education in the middle of war zones

Nature

Ancient surveying instrument found in Egypt

mardi 25 août 2026

Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02382-yThe earliest known example of a tool used to build in a straight line, and remembering an early trailblazer in radio communication in this week’s pick from the Nature (...)

Nature

AI-detection tools have made huge leaps forward — how good are they?

mardi 25 août 2026 par Miryam Naddaf, Richard Van Noorden

Nature, Published online: 25 August 2026; doi:10.1038/d41586-026-02569-3Scientists and publishers are testing a new breed of software that promises impressive accuracy at spotting AI-written text.

Nature