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Lineage and organ signals sequentially build organ intrinsic nervous systems

mercredi 13 mai 2026 par I-Uen Yvonne Hsu, Jia Zhao, Yingxin Lin, Yunshan Guo, Qian J. Xu, Yuancheng Shao, Ruiqi L. Wang, Dominic Yin, Kakali Ghoshal, Rida Mourad, Ambra Pozzi, Carmen M. Halabi, Lawrence H. Young, Hongyu Zhao, Le Zhang, Rui B. Chang

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10490-ySystems-level analyses of organ intrinsic nervous systems reveal that these networks are initially configured by lineage-dependent programmes, and their architecture and molecular identity are refined by intra-organ specific (...)

Nature

Gaussian boson sampling with 1,024 squeezed states in 8,176 modes

mercredi 13 mai 2026 par Hua-Liang Liu, Hao Su, Yu-Hao Deng, Si-Qiu Gong, Yi-Chao Gu, Hao-Yang Tang, Meng-Hao Jia, Qian Wei, Yu-Kun Song, Dong-Zhou Wang, Ming-Yang Zheng, Fa-Xi Chen, Li-Bo Li, Si-Yu Ren, Xue-Zhi Zhu, Mei-Hong Wang, Yao-Jian Chen, Yan-Fei Liu, Long-Sheng Song, Peng-Yu Yang, Jun-Shi Chen, Hong An, Lei Zhang, Lin Gan, Guang-wen Yang, Jia-Min Xu, Yu-Ming He, Hui Wang, Han-Sen Zhong, Ming-Cheng Chen, Xiao Jiang, Li Li, Nai-Le Liu, Xiao-Long Su, Qiang Zhang, Chao-Yang Lu, Jian-Wei Pan

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10523-6A programmable photonic quantum processor, Jiuzhang 4.0, incorporates 1,024 high-efficiency squeezed states into a hybrid spatial–temporal encoded 8,176-mode (...)

Nature

SNOR promotes translation restart after dormancy

mercredi 13 mai 2026 par Maciej Gluc, Higor Rosa, Maria Bozko, Lesley A. Turner, Cassidy R. Prince, Yelena Peskova, Heather A. Feaga, Kathleen L. Gould, Simone Mattei, Ahmad Jomaa

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10530-7High-resolution in situ cryo-electron tomography in Schizosaccharomyces pombe identifies SNOR protein, which binds to ribosomes during dormancy induced by glucose depletion, priming them for rapid reactivation of protein (...)

Nature

Ecotypes of triple-negative breast cancer in response to chemotherapy

mercredi 13 mai 2026 par Yun Yan, Yiyun Lin, Tapsi Kumar, Shanshan Bai, Aatish Thennavan, Jianzhuo Li, Emi Sei, Tuan Tran, Min Hu, Mitchell Rao, Chenling Tang, Siyuan He, Anna Casasent, Elizabeth Ravenberg, Gaiane Margishvili Rauch, Alyson R. Clayborn, Debu Tripathy, Alastair Thompson, Bora Lim, Lei Huo, Stacy Moulder, Clinton Yam, Nicholas Navin

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10469-9Treatment data for triple-negative breast cancer show the importance of macrophage subtypes and cancer-cell metaprograms for interferon signalling, HLA expression and cell cycle activity that are associated with a good (...)

Nature

Enamel proteins from six Homo erectus specimens across China

mercredi 13 mai 2026 par Qiaomei Fu, Zhongyou Wu, E. Andrew Bennett, Song Xing, Qiang Ji, Zhe Dong, Huiyun Rao, Xuejun Gu, Yizhao Dang, Jun Xing, Kai Zhou, Xiaotian Feng

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10478-8Palaeoproteomic analysis of ancient enamel proteins extracted from Middle Pleistocene Homo erectus specimens from the Zhoukoudian, Hexian and Sunjiadong sites in China suggests that they are a new genetic monogroup, and (...)

Nature

Twenty-first century emergence of alpine fire in Central African mountains

mercredi 13 mai 2026 par Andrea L. Mason, Eleanor M. B. Pereboom, Sarah J. Ivory, Richard S. Vachula, Meredith A. Kelly, Bob Nakileza, James M. Russell

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10511-wA twenty-first century fire is shown to be the first to have affected a high-elevation region in the central African mountains in the past 12,000 years, and previous burning at mid-elevations highlights the potential role of (...)

Nature

State media control influences large language models

mercredi 13 mai 2026 par Hannah Waight, Eddie Yang, Yin Yuan, Solomon Messing, Margaret E. Roberts, Brandon M. Stewart, Joshua A. Tucker

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10506-7Government-controlled media influences the output of large language models via their training data, and models queried in the languages of countries with lower media freedom show a stronger pro-regime valence than models (...)

Nature

Enhanced response of extreme compound events to cumulative CO₂ emissions

mercredi 13 mai 2026 par Jun Li, Yao Zhang, Philippe Ciais, Hongying Zhang, Zhaoli Wang, Hongwu Tang, Shilong Piao

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10544-1A new metric shows that compound climate extremes rise faster with cumulative CO2 emissions than models project, implying higher risks and smaller remaining carbon budgets for the 1.5 °C and 2 °C (...)

Nature

Long-term editing of brain circuits using an engineered electrical synapse

mercredi 13 mai 2026 par Elizabeth Ransey, Gwenaëlle E. Thomas, Elias M. Wisdom, Agustin Almoril-Porras, Ryan Bowman, Elise Adamson, Kathryn K. Walder-Christensen, Jesse A. White, Dalton N. Hughes, Hannah Schwennesen, Caly Ferguson, Kay M. Tye, Stephen D. Mague, Longgang Niu, Zhao-Wen Wang, Daniel Colón-Ramos, Rainbo Hultman, Nenad Bursac, Kafui Dzirasa

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10501-yConnexin proteins found in white perch fish were used to engineer synthetic electrical synapses, enabling precision circuit editing in mammals.

Nature

Stereoelectronic manipulation of ligands for perovskite solar cells

mercredi 13 mai 2026 par Tinghuan Yang, Erxin Zhao, Nan Wu, Xiaoming Chang, Chenqing Tian, Hai-Long Wang, Lu Zhang, Nannan Gu, Ting Nie, Ye Yang, Zheng Zhang, Tianfei Xu, Xin Chen, Shuang Wang, Tianqi Niu, Niansheng Xu, Chuang Ma, Haojin Li, Buyi Yan, Zicheng Ding, Shengzhong Frank Liu, Feng Gao, Kui Zhao

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10626-0Stereoelectronic manipulation of ligands for perovskite solar cells

Nature