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Neural basis of compositional control

mercredi 12 août 2026 par Assia Chericoni, Justin M. Fine, Taha S. Ismail, Gabriela Delgado Salazar, Melissa C. Franch, Elizabeth Mickiewicz, Ana G. Chavez, Eleonora Bartoli, Danika L. Paulo, Vaishnav Krishnan, Mohamed Hegazy, Alica M. Goldman, Lu Lin, Garrett P. Banks, Nisha Giridharan, Mohammed Hasen, Nicole R. Provenza, Andrew Watrous, Seng Bum Michael Yoo, Sameer A. Sheth, Benjamin Y. Hayden
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10896-8Behaviour of human participants in a prey-pursuit task reflects dynamic blending of goal-specific control policies, with hippocampus estimating latent states, anterior cingulate cortex orchestrating policy switches and (...)

Structural mechanism governing the directionality of bridge recombination

mercredi 12 août 2026 par Masahiro Hiraizumi, Januka S. Athukoralage, Nicholas T. Perry, Eisuke Tsujimoto, Nami Shiojiri, Naoto Nagahata, Lauren Lee, Gwanggyu Sun, Matthew G. Durrant, Sita S. Chandrasekaran, Silvana Konermann, Keitaro Yamashita, Patrick D. Hsu, Hiroshi Nishimasu
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10903-yCryo-electron microscopy structures show how IS621 bridge recombinase mediates DNA excision, explaining its natural preference for insertion and informing the design of programmable bridge-editing (...)

Species intraspecific variation drives tropical forest drought resistance

mercredi 12 août 2026 par Chris M. Smith-Martin, Robert Muscarella, Timothy J. Brodribb, María Uriarte
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10870-4Substantial intraspecific variation, together with species turnover, drives coordinated shifts in drought resistance such as increased embolism resistance and wider stomatal safety margins in drier (...)

Numerous bow shocks in the outer Helix Nebula

mercredi 12 août 2026 par Pieter van Dokkum, Roberto Abraham, William P. Bowman, Seery Chen, Steven R. Janssens, Deborah M. Lokhorst, Imad Pasha, Carter Rhea
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10724-zShocks in the eastern outskirts of the Helix Nebula, detected in Hα emission with the MOTHRA telescope, provide evidence for the recycling of fragmented stellar ejecta into the surrounding (...)

Evidence for the first globular cluster stellar stream beyond the Milky Way

mercredi 12 août 2026 par Julie Kiel Holm, Sarah Pearson, Jacob Nibauer, David J. Sand, Adrian M. Price-Whelan, Tjitske Starkenburg, David Hendel, Catherine Fielder
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10878-wDeep Hubble Space Telescope imaging of the ultra-diffuse galaxy UGC 9050-Dw1 reveals an extragalactic globular cluster stream, with analysis and modelling probing the rich dark matter content of the host (...)

Heterogeneous climatic controls on tropical-forest biomass

mercredi 12 août 2026 par Matheus Henrique Nunes, Helene C. Muller-Landau, Eric Bastos Görgens, Adrian Pascual, Ralph Dubayah
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10880-2An analysis of the relationships between aboveground biomass and various climatic factors in three major regions of tropical forest shows that understanding the complex interactions between climate, topography and soils is (...)

Superconducting 2D cuprate with a single CuO2 plane

mercredi 12 août 2026 par Hengsheng Luo, Dongjoon Song, Yijun Yu, Liguo Ma, Peng Cai, Ruidan Zhong, Yiwen Chen, Lin Zhao, Jian Shen, Dan Shahar, Xingjiang Zhou, Zhengyu Weng, Xian Hui Chen, Wei Ruan, Yuanbo Zhang
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10857-1A high-quality, pristine monolayer cuprate superconductor with a single CuO2 plane is fabricated and used to identify two quantum critical phenomena emerging between the Mott insulating phase and the superconducting (...)

Maternal influences on infant gut microbiome and health

mercredi 12 août 2026 par Trishla Sinha, Siobhan Brushett, Asier Fernández-Pato, Sanzhima Garmaeva, Sergio Andreu-Sánchez, Johanne E. Spreckels, Cyrus A. Mallon, Nataliia Kuzub, Milla Brandao Gois, Jiafei Wu, Marloes Kruk, Soesma A. Jankipersadsing, Jackie A. M. Dekens, Ranko Gacesa, Arnau Vich Vila, Corinna Bang, Corine Perenboom, Andre Franke, Hanne L. P. Tytgat, Sara Colombo Mottaz, Lilian Peters, Ank de Jonge, Henkjan J. Verkade, Morris A. Swertz, Cisca Wijmenga, Folkert Kuipers, Sicco Scherjon, Jan Sikkema, Aline B. Sprikkelman, Marlou L. A. de Kroon, Jelmer R. Prins, Sanne J. Gordijn, Gerard H. Koppelman, Sijmen A. Reijneveld, Milla F. Brandão-Gois, Marcel Bruinenberg, Anouk Marsman, Jingyuan Fu, Moran Yassour, Alexander Kurilshikov, Alexandra Zhernakova
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10922-9The maternal gut microbiome is a predictor of infant eczema.

In vivo genome-wide CRISPR screens of human T cells in solid tumours

mercredi 12 août 2026 par Qi Liu, Peixin Amy Chen, Esha Urs, Shimin Zhang, Maya M. Arce, Charlotte H. Wang, Jun Yan, Vinh Q. Nguyen, Zhongmei Li, Jin Seo, Nupura Kale, Fanglue Peng, Yikai Luo, Laine Goudy, Taylor N. LaFlam, Haixia Zhong, Chandrima Modak, Emma Dann, Jae Hyung Jung, Amanda Kirane, Allison Betof Warner, Boi Bryant Quach, Zinaida Good, Brian R. Shy, Eric Shifrut, Sagar P. Bapat, Greg M. Allen, Justin Eyquem, Katherine Fuh, Stacie E. Dodgson, Jason G. Cyster, Alexander Marson, Julia Carnevale
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10906-9An in vivo model that is able to recover human T cells from solid tumours can identify targets to help improve CAR T cell antitumour activity.

Biomarkers of nivolumab benefit in resectable non-small cell lung cancer

mercredi 12 août 2026 par Tina Cascone, Mark M. Awad, Jonathan D. Spicer, Jie He, Shun Lu, Fumihiro Tanaka, Robin Cornelissen, Lubos B. Petruzelka, Yang Gao, Jean-Louis Pujol, Hiroyuki Ito, Ludmila de Oliveira Muniz Koch, Tudor-Eliade Ciuleanu, Lin Wu, Sabine Bohnet, Yasutaka Watanabe, Janis M. Taube, Julie Stein Deutsch, Cinthya Coronado Erdmann, Stephanie Meadows-Shropshire, Jaclyn Neely, Virginia Ip, Yu-Han Hung, Padma Sathyanarayana, Sumeena Bhatia, Katherine Chu, Steven I. Blum, Stefano Lucherini, Nathanial Eddy, Akshay Yadav, Mariano Provencio
Nature, Published online: 12 August 2026; doi:10.1038/s41586-026-10925-6Potential predictive biomarkers of perioperative nivolumab therapy benefit in non-small cell lung cancer are identified from evaluable participants in the CheckMate 77T (...)

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