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Nature is the international weekly journal of science : a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and how science impacts upon all aspects of society and life.

Articles les plus récents

Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile

mercredi 6 avril 2022 par Xinyun Cao, Hande Boyaci, James Chen, Yu Bao, Robert Landick, Elizabeth A. Campbell
Nature, Published online: 06 April 2022; doi:10.1038/s41586-022-04545-zStructural analysis of Clostridioides difficile RNA polymerase in complex with fidaxomicin combined with biochemical, genetic and bioinformatic analyses identifies a key residue that determines fidaxomicin (...)

UV absorption by silicate cloud precursors in ultra-hot Jupiter WASP-178b

mercredi 6 avril 2022 par Joshua D. Lothringer, David K. Sing, Zafar Rustamkulov, Hannah R. Wakeford, Kevin B. Stevenson, Nikolay Nikolov, Panayotis Lavvas, Jessica J. Spake, Autumn T. Winch
Nature, Published online: 06 April 2022; doi:10.1038/s41586-022-04453-2Analysis is presented that indicates that there is strong evidence that SiO or Mg, the major constituents of silicate condensates, must be present in gaseous form in the atmosphere of ultra-hot Jupiter (...)

A joint NCBI and EMBL-EBI transcript set for clinical genomics and research

mercredi 6 avril 2022 par Joannella Morales, Shashikant Pujar, Jane E. Loveland, Alex Astashyn, Ruth Bennett, Andrew Berry, Eric Cox, Claire Davidson, Olga Ermolaeva, Catherine M. Farrell, Reham Fatima, Laurent Gil, Tamara Goldfarb, Jose M. Gonzalez, Diana Haddad, Matthew Hardy, Toby Hunt, John Jackson, Vinita S. Joardar, Michael Kay, Vamsi K. Kodali, Kelly M. McGarvey, Aoife McMahon, Jonathan M. Mudge, Daniel N. Murphy, Michael R. Murphy, Bhanu Rajput, Sanjida H. Rangwala, Lillian D. Riddick, Françoise Thibaud-Nissen, Glen Threadgold, Anjana R. Vatsan, Craig Wallin, David Webb, Paul Flicek, Ewan Birney, Kim D. Pruitt, Adam Frankish, Fiona Cunningham, Terence D. Murphy
Nature, Published online: 06 April 2022; doi:10.1038/s41586-022-04558-8Matched Annotation from NCBI and EMBL-EBI (MANE) delivers joint transcript sets from Ensembl/GENCODE and RefSeq for standardizing variant reporting in clinical genomics and (...)

Search for Majorana neutrinos exploiting millikelvin cryogenics with CUORE

mercredi 6 avril 2022 par D. Q. Adams, C. Alduino, K. Alfonso, F. T. Avignone III, O. Azzolini, G. Bari, F. Bellini, G. Benato, M. Beretta, M. Biassoni, A. Branca, C. Brofferio, C. Bucci, J. Camilleri, A. Caminata, A. Campani, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Cardani, P. Carniti, N. Casali, E. Celi, D. Chiesa, M. Clemenza, S. Copello, O. Cremonesi, R. J. Creswick, A. D’Addabbo, I. Dafinei, S. Dell’Oro, S. Di Domizio, V. Dompè, D. Q. Fang, G. Fantini, M. Faverzani, E. Ferri, F. Ferroni, E. Fiorini, M. A. Franceschi, S. J. Freedman, S. H. Fu, B. K. Fujikawa, A. Giachero, L. Gironi, A. Giuliani, P. Gorla, C. Gotti, T. D. Gutierrez, K. Han, E. V. Hansen, K. M. Heeger, R. G. Huang, H. Z. Huang, J. Johnston, G. Keppel, Yu. G. Kolomensky, C. Ligi, R. Liu, L. Ma, Y. G. Ma, L. Marini, R. H. Maruyama, D. Mayer, Y. Mei, N. Moggi, S. Morganti, T. Napolitano, M. Nastasi, J. Nikkel, C. Nones, E. B. Norman, A. Nucciotti, I. Nutini, T. O’Donnell, J. L. Ouellet, S. Pagan, C. E. Pagliarone, L. Pagnanini, M. Pallavicini, L. Pattavina, M. Pavan, G. Pessina, V. Pettinacci, C. Pira, S. Pirro, S. Pozzi, E. Previtali, A. Puiu, C. Rosenfeld, C. Rusconi, M. Sakai, S. Sangiorgio, B. Schmidt, N. D. Scielzo, V. Sharma, V. Singh, M. Sisti, D. Speller, P. T. Surukuchi, L. Taffarello, F. Terranova, C. Tomei, K. J. Vetter, M. Vignati, S. L. Wagaarachchi, B. S. Wang, B. Welliver, J. Wilson, K. Wilson, L. A. Winslow, S. Zimmermann, S. Zucchelli
Nature, Published online: 06 April 2022; doi:10.1038/s41586-022-04497-4The CUORE experiment finds no evidence for neutrinoless double beta decay after operating a large cryogenic TeO2 calorimeter stably for several years in an extreme low-radiation environment at a temperature of 10 (...)

Two defence systems eliminate plasmids from seventh pandemic Vibrio cholerae

mercredi 6 avril 2022 par Milena Jaskólska, David W. Adams, Melanie Blokesch
Nature, Published online: 06 April 2022; doi:10.1038/s41586-022-04546-yTwo defence systems are identified in pandemic Vibrio cholerae that act both cooperatively and independently to eliminate invasive plasmids and bacteriophages.

Structure deformation and curvature sensing of PIEZO1 in lipid membranes

mercredi 6 avril 2022 par Xuzhong Yang, Chao Lin, Xudong Chen, Shouqin Li, Xueming Li, Bailong Xiao
Nature, Published online: 06 April 2022; doi:10.1038/s41586-022-04574-8Cryo-electron microscopy structures of PIEZO1 in liposome vesicles in curved and flattened conformations demonstrate the high deformability underlying the high mechanosensitivity and ion selectivity of PIEZO channel (...)

COVID vaccine plus infection can lead to months of immunity

mercredi 6 avril 2022 par Saima May Sidik
Nature, Published online: 06 April 2022; doi:10.1038/d41586-022-00961-3Findings from Brazil, Sweden and the United Kingdom show that before the advent of Omicron, vaccination benefited even those who had had a bout of COVID-19.

The countries maintaining research ties with Russia despite Ukraine

mercredi 6 avril 2022 par Smriti Mallapaty, T. V. Padma, Emiliano Rodríguez Mega, Richard Van Noorden, Ehsan Masood
Nature, Published online: 06 April 2022; doi:10.1038/d41586-022-00945-3Many Western nations are severing scientific links — but it’s a different story in China, India and South Africa.

Mapping the energetic and allosteric landscapes of protein binding domains

mercredi 6 avril 2022 par Andre J. Faure, Júlia Domingo, Jörn M. Schmiedel, Cristina Hidalgo-Carcedo, Guillaume Diss, Ben Lehner
Nature, Published online: 06 April 2022; doi:10.1038/s41586-022-04586-4An approach that combines deep mutational scanning with neural network-based thermodynamic modelling is used to provide comprehensive maps of the energetic and allosteric effects of mutations in two common protein (...)

Brain charts for the human lifespan

mercredi 6 avril 2022 par R. A. I. Bethlehem, J. Seidlitz, S. R. White, J. W. Vogel, K. M. Anderson, C. Adamson, S. Adler, G. S. Alexopoulos, E. Anagnostou, A. Areces-Gonzalez, D. E. Astle, B. Auyeung, M. Ayub, J. Bae, G. Ball, S. Baron-Cohen, R. Beare, S. A. Bedford, V. Benegal, F. Beyer, J. Blangero, M. Blesa Cábez, J. P. Boardman, M. Borzage, J. F. Bosch-Bayard, N. Bourke, V. D. Calhoun, M. M. Chakravarty, C. Chen, C. Chertavian, G. Chetelat, Y. S. Chong, J. H. Cole, A. Corvin, M. Costantino, E. Courchesne, F. Crivello, V. L. Cropley, J. Crosbie, N. Crossley, M. Delarue, R. Delorme, S. Desrivieres, G. A. Devenyi, M. A. Di Biase, R. Dolan, K. A. Donald, G. Donohoe, K. Dunlop, A. D. Edwards, J. T. Elison, C. T. Ellis, J. A. Elman, L. Eyler, D. A. Fair, E. Feczko, P. C. Fletcher, P. Fonagy, C. E. Franz, L. Galan-Garcia, A. Gholipour, J. Giedd, J. H. Gilmore, D. C. Glahn, I. M. Goodyer, P. E. Grant, N. A. Groenewold, F. M. Gunning, R. E. Gur, R. C. Gur, C. F. Hammill, O. Hansson, T. Hedden, A. Heinz, R. N. Henson, K. Heuer, J. Hoare, B. Holla, A. J. Holmes, R. Holt, H. Huang, K. Im, J. Ipser, C. R. Jack Jr, A. P. Jackowski, T. Jia, K. A. Johnson, P. B. Jones, D. T. Jones, R. S. Kahn, H. Karlsson, L. Karlsson, R. Kawashima, E. A. Kelley, S. Kern, K. W. Kim, M. G. Kitzbichler, W. S. Kremen, F. Lalonde, B. Landeau, S. Lee, J. Lerch, J. D. Lewis, J. Li, W. Liao, C. Liston, M. V. Lombardo, J. Lv, C. Lynch, T. T. Mallard, M. Marcelis, R. D. Markello, S. R. Mathias, B. Mazoyer, P. McGuire, M. J. Meaney, A. Mechelli, N. Medic, B. Misic, S. E. Morgan, D. Mothersill, J. Nigg, M. Q. W. Ong, C. Ortinau, R. Ossenkoppele, M. Ouyang, L. Palaniyappan, L. Paly, P. M. Pan, C. Pantelis, M. M. Park, T. Paus, Z. Pausova, D. Paz-Linares, A. Pichet Binette, K. Pierce, X. Qian, J. Qiu, A. Qiu, A. Raznahan, T. Rittman, A. Rodrigue, C. K. Rollins, R. Romero-Garcia, L. Ronan, M. D. Rosenberg, D. H. Rowitch, G. A. Salum, T. D. Satterthwaite, H. L. Schaare, R. J. Schachar, A. P. Schultz, G. Schumann, M. Schöll, D. Sharp, R. T. Shinohara, I. Skoog, C. D. Smyser, R. A. Sperling, D. J. Stein, A. Stolicyn, J. Suckling, G. Sullivan, Y. Taki, B. Thyreau, R. Toro, N. Traut, K. A. Tsvetanov, N. B. Turk-Browne, J. J. Tuulari, C. Tzourio, É. Vachon-Presseau, M. J. Valdes-Sosa, P. A. Valdes-Sosa, S. L. Valk, T. van Amelsvoort, S. N. Vandekar, L. Vasung, L. W. Victoria, S. Villeneuve, A. Villringer, P. E. Vértes, K. Wagstyl, Y. S. Wang, S. K. Warfield, V. Warrier, E. Westman, M. L. Westwater, H. C. Whalley, A. V. Witte, N. Yang, B. Yeo, H. Yun, A. Zalesky, H. J. Zar, A. Zettergren, J. H. Zhou, H. Ziauddeen, A. Zugman, X. N. Zuo, C. Rowe, G. B. Frisoni, E. T. Bullmore, A. F. Alexander-Bloch
Nature, Published online: 06 April 2022; doi:10.1038/s41586-022-04554-yMRI data from more than 100 studies have been aggregated to yield new insights about brain development and ageing, and create an interactive open resource for comparison of brain structures throughout the human lifespan, (...)

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