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Nature

Nature is the international weekly journal of science : a magazine style journal that publishes full-length research papers in all disciplines of science, as well as News and Views, reviews, news, features, commentaries, web focuses and more, covering all branches of science and how science impacts upon all aspects of society and life.

Articles les plus récents

Lifelong multilineage contribution by embryonic-born blood progenitors

mercredi 15 juin 2022 par Sachin H. Patel, Constantina Christodoulou, Caleb Weinreb, Qi Yu, Edroaldo Lummertz da Rocha, Brian J. Pepe-Mooney, Sarah Bowling, Li Li, Fernando G. Osorio, George Q. Daley, Fernando D. Camargo
Nature, Published online: 15 June 2022; doi:10.1038/s41586-022-04804-zIn situ barcoding and fate mapping in mice reveals that an early wave of progenitor specification, driven by embryonic multipotent progenitor cells, gives rise to adult blood independently of haematopoietic stem (...)

Synthesis of a monolayer fullerene network

mercredi 15 juin 2022 par Lingxiang Hou, Xueping Cui, Bo Guan, Shaozhi Wang, Ruian Li, Yunqi Liu, Daoben Zhu, Jian Zheng
Nature, Published online: 15 June 2022; doi:10.1038/s41586-022-04771-5Using an interlayer bonding cleavage strategy, a two-dimensional monolayer fullerene network is prepared; its moderate bandgap makes it a potential candidate for use in two-dimensional electronic (...)

Caspase-7 activates ASM to repair gasdermin and perforin pores

mercredi 15 juin 2022 par Kengo Nozaki, Vivien I. Maltez, Manira Rayamajhi, Alan L. Tubbs, Joseph E. Mitchell, Carolyn A. Lacey, Carissa K. Harvest, Lupeng Li, William T. Nash, Heather N. Larson, Benjamin D. McGlaughon, Nathaniel J. Moorman, Michael G. Brown, Jason K. Whitmire, Edward A. Miao
Nature, Published online: 15 June 2022; doi:10.1038/s41586-022-04825-8Caspase-7 cleaves and activates acid sphingomyelinase (ASM), which promotes the repair of gasdermin pores and thereby delays pore-driven lysis to allow other processes such as extrusion or apoptosis to occur before cell (...)

Signatures of copy number alterations in human cancer

mercredi 15 juin 2022 par Christopher D. Steele, Ammal Abbasi, S. M. Ashiqul Islam, Amy L. Bowes, Azhar Khandekar, Kerstin Haase, Shadi Hames-Fathi, Dolapo Ajayi, Annelien Verfaillie, Pawan Dhami, Alex McLatchie, Matt Lechner, Nicholas Light, Adam Shlien, David Malkin, Andrew Feber, Paula Proszek, Tom Lesluyes, Fredrik Mertens, Adrienne M. Flanagan, Maxime Tarabichi, Peter Van Loo, Ludmil B. Alexandrov, Nischalan Pillay
Nature, Published online: 15 June 2022; doi:10.1038/s41586-022-04738-6A new framework enables a pan-cancer reference set of copy number signatures derived from allele-specific profiles from different experimental assays.

Peptidoglycan maturation controls outer membrane protein assembly

mercredi 15 juin 2022 par Gideon Mamou, Federico Corona, Ruth Cohen-Khait, Nicholas G. Housden, Vivian Yeung, Dawei Sun, Pooja Sridhar, Manuel Pazos, Timothy J. Knowles, Colin Kleanthous, Waldemar Vollmer
Nature, Published online: 15 June 2022; doi:10.1038/s41586-022-04834-7Peptidoglycan stem peptides in the Gram-negative bacterial cell wall regulate the insertion of essential outer membrane proteins, thus representing a potential target for antibiotic (...)

A population of ultraviolet-dim protoclusters detected in absorption

mercredi 15 juin 2022 par Andrew B. Newman, Gwen C. Rudie, Guillermo A. Blanc, Mahdi Qezlou, Simeon Bird, Daniel D. Kelson, Victoria Pérez, Enrico Congiu, Brian C. Lemaux, Alan Dressler, John S. Mulchaey
Nature, Published online: 15 June 2022; doi:10.1038/s41586-022-04681-6Lyman-α absorption observations from the Las Campanas Observatory are used to find a population of ultraviolet-dim protoclusters that contain few galaxies compared with their analogues in cosmological (...)

Deciphering the immunopeptidome in vivo reveals new tumour antigens

mercredi 15 juin 2022 par Alex M. Jaeger, Lauren E. Stopfer, Ryuhjin Ahn, Emma A. Sanders, Demi A. Sandel, William A. Freed-Pastor, William M. Rideout III, Santiago Naranjo, Tim Fessenden, Kim B. Nguyen, Peter S. Winter, Ryan E. Kohn, Peter M. K. Westcott, Jason M. Schenkel, Sean-Luc Shanahan, Alex K. Shalek, Stefani Spranger, Forest M. White, Tyler Jacks
Nature, Published online: 15 June 2022; doi:10.1038/s41586-022-04839-2A newly developed genetically engineered mouse model enables the analysis of specific antigen presentation in vivo, providing insights into the tumour immunopeptidome and cancer (...)

The source of the Black Death in fourteenth-century central Eurasia

mercredi 15 juin 2022 par Maria A. Spyrou, Lyazzat Musralina, Guido A. Gnecchi Ruscone, Arthur Kocher, Pier-Giorgio Borbone, Valeri I. Khartanovich, Alexandra Buzhilova, Leyla Djansugurova, Kirsten I. Bos, Denise Kühnert, Wolfgang Haak, Philip Slavin, Johannes Krause
Nature, Published online: 15 June 2022; doi:10.1038/s41586-022-04800-3The source of the Black Death in fourteenth-century central Eurasia

Superconducting-qubit readout via low-backaction electro-optic transduction

mercredi 15 juin 2022 par R. D. Delaney, M. D. Urmey, S. Mittal, B. M. Brubaker, J. M. Kindem, P. S. Burns, C. A. Regal, K. W. Lehnert
Nature, Published online: 15 June 2022; doi:10.1038/s41586-022-04720-2Readout of a superconducting qubit embedded in a circuit quantum electrodynamics architecture is demonstrated at optical frequencies through a low-noise electro-optomechanical (...)

A pan-cancer compendium of chromosomal instability

mercredi 15 juin 2022 par Ruben M. Drews, Barbara Hernando, Maxime Tarabichi, Kerstin Haase, Tom Lesluyes, Philip S. Smith, Lena Morrill Gavarró, Dominique-Laurent Couturier, Lydia Liu, Michael Schneider, James D. Brenton, Peter Van Loo, Geoff Macintyre, Florian Markowetz
Nature, Published online: 15 June 2022; doi:10.1038/s41586-022-04789-9Copy number signatures characterize different types of chromosomal instability and predict drug response.

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