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Topological chiral crystals with helicoid-arc quantum states

mercredi 20 mars 2019 par Daniel S. Sanchez, Ilya Belopolski, Tyler A. Cochran, Xitong Xu, Jia-Xin Yin, Guoqing Chang, Weiwei Xie, Kaustuv Manna, Vicky Süß, Cheng-Yi Huang, Nasser Alidoust, Daniel Multer, Songtian S. Zhang, Nana Shumiya, Xirui Wang, Guang-Qiang Wang, Tay-Rong Chang, Claudia Felser, Su-Yang Xu, Shuang Jia, Hsin Lin, M. Zahid Hasan
Topological chiral crystals with helicoid-arc quantum states Topological chiral crystals with helicoid-arc quantum states, Published online: 20 March 2019; doi:10.1038/s41586-019-1037-2Angle-resolved photoemission spectroscopy measurements reveal that CoSi and RhSi are nearly ideal topological (...)

Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase

mercredi 20 mars 2019 par Steffi Herold, Jacqueline Kalb, Gabriele Büchel, Carsten P. Ade, Apoorva Baluapuri, Jiajia Xu, Jan Koster, Daniel Solvie, Anne Carstensen, Christina Klotz, Sabrina Rodewald, Christina Schülein-Völk, Matthias Dobbelstein, Elmar Wolf, Jan Molenaar, Rogier Versteeg, Susanne Walz, Martin Eilers
Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase, Published online: 20 March 2019; doi:10.1038/s41586-019-1030-9In human neuroblastoma tumours, MYCN is engaged in a USP11–BRCA1-dependent (...)

The expanding landscape of ‘oncohistone’ mutations in human cancers

mercredi 20 mars 2019 par Benjamin A. Nacev, Lijuan Feng, John D. Bagert, Agata E. Lemiesz, JianJiong Gao, Alexey A. Soshnev, Ritika Kundra, Nikolaus Schultz, Tom W. Muir, C. David Allis
The expanding landscape of ‘oncohistone’ mutations in human cancers The expanding landscape of ‘oncohistone’ mutations in human cancers, Published online: 20 March 2019; doi:10.1038/s41586-019-1038-1The characterization of missense histone mutations that occur across several cancer types provides (...)

Neoantigen-directed immune escape in lung cancer evolution

mercredi 20 mars 2019 par Rachel Rosenthal, Elizabeth Larose Cadieux, Roberto Salgado, Maise Al Bakir, David A. Moore, Crispin T. Hiley, Tom Lund, Miljana Tanić, James L. Reading, Kroopa Joshi, Jake Y. Henry, Ehsan Ghorani, Gareth A. Wilson, Nicolai J. Birkbak, Mariam Jamal-Hanjani, Selvaraju Veeriah, Zoltan Szallasi, Sherene Loi, Matthew D. Hellmann, Andrew Feber, Benny Chain, Javier Herrero, Sergio A. Quezada, Jonas Demeulemeester, Peter Van Loo, Stephan Beck, Nicholas McGranahan, Charles Swanton, Justyna Czyzewska-Khan, Diana Johnson, Joanne Laycock, Pat Gorman, Robert E. Hynds, Gareth Wilson, Thomas B. K. Watkins, Mickael Escudero, Aengus Stewart, Andrew Rowan, Crispin Hiley, Christopher Abbosh, Jacki Goldman, Richard Kevin Stone, Tamara Denner, Sophia Ward, Emma Nye, Assma Ben Aissa, Yien Ning Sophia Wong, Andy Georgiou, Sergio Quezada, John A. Hartley, Helen L. Lowe, David Lawrence, Martin Hayward, Nikolaos Panagiotopoulos, Mary Falzon, Elaine Borg, Teresa Marafioti, Sam M. Janes, Martin Forster, Tanya Ahmad, Siow Ming Lee, Dionysis Papadatos-Pastos, Dawn Carnell, Ruheena Mendes, Jeremy George, Asia Ahmed, Magali Taylor, Junaid Choudhary, Yvonne Summers, Raffaele Califano, Paul Taylor, Rajesh Shah, Piotr Krysiak, Kendadai Rammohan, Eustace Fontaine, Richard Booton, Matthew Evison, Phil Crosbie, Stuart Moss, Leena Joseph, Paul Bishop, Anne Marie Quinn, Helen Doran, Angela Leek, Phil Harrison, Katrina Moore, Rachael Waddington, Juliette Novasio, Fiona Blackhall, Jane Rogan, Elaine Smith, Caroline Dive, Jonathan Tugwood, Ged Brady, Dominic G. Rothwell, Jackie Pierce, Sakshi Gulati, Babu Naidu, Gerald Langman, Simon Trotter, Hollie Bancroft, Amy Kerr, Salma Kadiri, Gary Middleton, Madava Djearaman, Dean Fennell, Jacqui A. Shaw, John Le Quesne, Apostolos Nakas, Sridhar Rathinam, William Monteiro, Hilary Marshall, Louise Nelson, Joan Riley, Lindsay Primrose, Luke Martinson, Girija Anand, Sajid Khan, Marianne Nicolson, Keith Kerr, Shirley Palmer, Hardy Remmen, Joy Miller, Keith Buchan, Mahendran Chetty, Lesley Gomersall, Jason Lester, Fiona Morgan, Haydn Adams, Helen Davies, Malgorzata Kornaszewska, Richard Attanoos, Sara Lock, Mairead MacKenzie, Maggie Wilcox, Harriet Bell, Allan Hackshaw, Yenting Ngai, Sean Smith, Nicole Gower, Christian Ottensmeier, Serena Chee, Benjamin Johnson, Aiman Alzetani, Emily Shaw, Eric Lim, Paulo De Sousa, Monica Tavares Barbosa, Alex Bowman, Simon Jordan, Alexandra Rice, Hilgardt Raubenheimer, Harshil Bhayani, Morag Hamilton, Natalie Mensah, Lyn Ambrose, Anand Devaraj, Hema Chavan, Andrew G. Nicholson, Kelvin Lau, Michael Sheaff, Peter Schmid, John Conibear, Veni Ezhil, Vineet Prakash, Peter Russell, Teresa Light, Tracey Horey, Sarah Danson, Jonathan Bury, John Edwards, Jennifer Hill, Sue Matthews, Yota Kitsanta, Kim Suvarna, Patricia Fisher, Michael Shackcloth, John Gosney, Sarah Feeney, Julius Asante-Siaw, Kim Ryanna, Alan Dawson, Mohamad Tuffail, Amrita Bajaj, Jan Brozik, Harriet Walter, Nicolas Carey, Gillian Price, Kayleigh Gilbert, Joanne Webb, Akshay Patel, Anshuman Chaturvedi, Felice Granato, Katie Baker, Mathew Carter, Lynsey Priest, Matthew G. Krebs, Colin Lindsay, Fabio Gomes, Francesca Chemie, Robert George, Davide Patrini, Reena Khiroya, Penny Shaw, Marcin Skrzypski, Mariana Werner Sunderland, James L. Reading, Carmella Beastall, Nagina Mangal, Karl Peggs, Emilia Lim, Maise Al-Bakir, Neal Navani, Marco Scarci, Leah Ensell, Dhruva Biswas, Maryam Razaq, Jerome Nicod, Saioa Lopez, Ariana Huebner, Michelle Dietzen, Thanos Mourikis, Toyin Adefila-Ideozu, Sofina Begum, Henriette Klein, Aleksander Mani, Soraia Carvalho, Daniel Kaniu, Cristina Realingo, Mpho Malima, Sarah Booth, Louise Lim, Jagan Rao, Sara Tenconi, Laura Socci, Faith Kibutu, Michael Agyemang, Robin Young, Kevin G. Blyth, Craig Dick, Alan Kirk, Andrew Kidd
Neoantigen-directed immune escape in lung cancer evolution Neoantigen-directed immune escape in lung cancer evolution, Published online: 20 March 2019; doi:10.1038/s41586-019-1032-7RNA sequencing data and tumour pathology observations of non-small-cell lung cancers indicate that the immune cell (...)

Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules

mercredi 20 mars 2019 par Benjamin Falcon, Jasenko Zivanov, Wenjuan Zhang, Alexey G. Murzin, Holly J. Garringer, Ruben Vidal, R. Anthony Crowther, Kathy L. Newell, Bernardino Ghetti, Michel Goedert, Sjors H. W. Scheres
Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules, Published online: 20 March 2019; doi:10.1038/s41586-019-1026-5Cryo-electron microscopy structures of tau (...)

Particle robotics based on statistical mechanics of loosely coupled components

mercredi 20 mars 2019 par Shuguang Li, Richa Batra, David Brown, Hyun-Dong Chang, Nikhil Ranganathan, Chuck Hoberman, Daniela Rus, Hod Lipson
Particle robotics based on statistical mechanics of loosely coupled components Particle robotics based on statistical mechanics of loosely coupled components, Published online: 20 March 2019; doi:10.1038/s41586-019-1022-9A stochastic robotic system shows deterministic behaviour—such as locomotion, (...)

Van der Waals integration before and beyond two-dimensional materials

mercredi 20 mars 2019 par Yuan Liu, Yu Huang, Xiangfeng Duan
Van der Waals integration before and beyond two-dimensional materials Van der Waals integration before and beyond two-dimensional materials, Published online: 20 March 2019; doi:10.1038/s41586-019-1013-xRecent advances and future directions in the use of van der Waals integration beyond (...)

Métaux antibactériens inspirés par la nature

mardi 19 mars 2019 — Physique
Les scientifiques ont mis au point une surface métallique texturée au laser et imperméable aux liquides pour aider à améliorer la productivité et à réduire les coûts dans l'industrie...

Quelle est la masse de la Voie lactée?

mardi 19 mars 2019 — Astrophysique
La NASA et l'Agence spatiale européenne ont uni leurs efforts pour répondre à une question apparemment insoluble: quelle est la masse de la Voie lactée? Le panorama de la Voie Lactée....

Une riche cité découverte aux portes de la Mésopotamie

mardi 19 mars 2019 — Autres sujets
Au Kurdistan d'Irak, les fouilles menées par une mission archéologique française ont révélé une ville antique inédite, sur le site de Kunara. Vers la fin du IIIe millénaire av. J.-C., cette...

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