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Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

jeudi 30 juillet 2020 par Noe B. Mercado, Roland Zahn, Frank Wegmann, Carolin Loos, Abishek Chandrashekar, Jingyou Yu, Jinyan Liu, Lauren Peter, Katherine McMahan, Lisa H. Tostanoski, Xuan He, David R. Martinez, Lucy Rutten, Rinke Bos, Danielle van Manen, Jort Vellinga, Jerome Custers, Johannes P. Langedijk, Ted Kwaks, Mark J. G. Bakkers, David Zuijdgeest, Sietske K. Rosendahl Huber, Caroline Atyeo, Stephanie Fischinger, John S. Burke, Jared Feldman, Blake M. Hauser, Timothy M. Caradonna, Esther A. Bondzie, Gabriel Dagotto, Makda S. Gebre, Emily Hoffman, Catherine Jacob-Dolan, Marinela Kirilova, Zhenfeng Li, Zijin Lin, Shant H. Mahrokhian, Lori F. Maxfield, Felix Nampanya, Ramya Nityanandam, Joseph P. Nkolola, Shivani Patel, John D. Ventura, Kaylee Verrington, Huahua Wan, Laurent Pessaint, Alex Van Ry, Kelvin Blade, Amanda Strasbaugh, Mehtap Cabus, Renita Brown, Anthony Cook, Serge Zouantchangadou, Elyse Teow, Hanne Andersen, Mark G. Lewis, Yongfei Cai, Bing Chen, Aaron G. Schmidt, R. Keith Reeves, Ralph S. Baric, Douglas A. Lauffenburger, Galit Alter, Paul Stoffels, Mathai Mammen, Johan Van Hoof, Hanneke Schuitemaker, Dan H. Barouch
Nature, Published online: 30 July 2020; doi:10.1038/s41586-020-2607-zSingle-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques

Publisher Correction: Discovery and engineering of colchicine alkaloid biosynthesis

jeudi 30 juillet 2020 par Ryan S. Nett, Warren Lau, Elizabeth S. Sattely
Nature, Published online: 30 July 2020; doi:10.1038/s41586-020-2606-0Publisher Correction: Discovery and engineering of colchicine alkaloid biosynthesis

Should virus-naming rules change during a pandemic? The question divides virologists

jeudi 30 juillet 2020 par Smriti Mallapaty
Nature, Published online: 30 July 2020; doi:10.1038/d41586-020-02243-2Researchers say now is bad time to introduce a system for naming viral species, when scientists are focused on the coronavirus outbreak.

Daily Briefing: NASA’s Perseverance rover blasts off for Mars

jeudi 30 juillet 2020 par Emma Stoye
Nature, Published online: 30 July 2020; doi:10.1038/d41586-020-02271-yThe most complex rover ever sent to the red planet will attempt to collect rock samples for return to Earth. Plus: the origin of Stonehenge’s giant stones, and three questions to ask yourself before quitting your (...)

DNA targeting and interference by a bacterial Argonaute nuclease

jeudi 30 juillet 2020 par Anton Kuzmenko, Anastasiya Oguienko, Daria Esyunina, Denis Yudin, Mayya Petrova, Alina Kudinova, Olga Maslova, Maria Ninova, Sergei Ryazansky, David Leach, Alexei A. Aravin, Andrey Kulbachinskiy
Nature, Published online: 30 July 2020; doi:10.1038/s41586-020-2605-1DNA targeting and interference by a bacterial Argonaute nuclease

This super ‘sponge’ releases steam when the Sun shines

jeudi 30 juillet 2020
Nature, Published online: 30 July 2020; doi:10.1038/d41586-020-02255-yA curious gel can soak up water vapour from the air and swell to enormous size without bursting.

University redundancies, furloughs and pay cuts might loom amid the pandemic, survey finds

jeudi 30 juillet 2020 par Madeline Bodin
Nature, Published online: 30 July 2020; doi:10.1038/d41586-020-02265-wAcademic administrators are mostly optimistic about the effects of COVID-19 on institutional finances, but others predict tough times.

Gut microbes and stress team up to make a painful disease worse

jeudi 30 juillet 2020
Nature, Published online: 30 July 2020; doi:10.1038/d41586-020-02263-yA type of gut bacterium worsens the inflammatory response and cardiovascular problems in mice.

Microbiota-derived metabolite promotes HDAC3 activity in the gut

jeudi 30 juillet 2020 par Shu-en Wu, Seika Hashimoto-Hill, Vivienne Woo, Emily M. Eshleman, Jordan Whitt, Laura Engleman, Rebekah Karns, Lee A. Denson, David B. Haslam, Theresa Alenghat
Nature, Published online: 30 July 2020; doi:10.1038/s41586-020-2604-2Microbiota-derived metabolite promotes HDAC3 activity in the gut

ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

jeudi 30 juillet 2020 par Neeltje van Doremalen, Teresa Lambe, Alexandra Spencer, Sandra Belij-Rammerstorfer, Jyothi N. Purushotham, Julia R. Port, Victoria A. Avanzato, Trenton Bushmaker, Amy Flaxman, Marta Ulaszewska, Friederike Feldmann, Elizabeth R. Allen, Hannah Sharpe, Jonathan Schulz, Myndi Holbrook, Atsushi Okumura, Kimberly Meade-White, Lizzette Pérez-Pérez, Nick J. Edwards, Daniel Wright, Cameron Bissett, Ciaran Gilbride, Brandi N. Williamson, Rebecca Rosenke, Dan Long, Alka Ishwarbhai, Reshma Kailath, Louisa Rose, Susan Morris, Claire Powers, Jamie Lovaglio, Patrick W. Hanley, Dana Scott, Greg Saturday, Emmie de Wit, Sarah C. Gilbert, Vincent J. Munster
Nature, Published online: 30 July 2020; doi:10.1038/s41586-020-2608-yChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

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