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Articles les plus récents

RNA therapies explained

mercredi 16 octobre 2019 par Sarah DeWeerdt
Nature, Published online: 16 October 2019; doi:10.1038/d41586-019-03068-4Treatments that target RNA or deliver it to cells fall into three broad categories, with hybrid approaches also emerging.

Patisiran’s path to approval as an RNA therapy

mercredi 16 octobre 2019 par Carlos Heras-Palou
Nature, Published online: 16 October 2019; doi:10.1038/d41586-019-03070-wCarlos Heras-Palou explains his part in making the first RNA-interference therapeutic available to people with rare diseases.

Why rare genetic diseases are a logical focus for RNA therapies

mercredi 16 octobre 2019 par Liam Drew
Nature, Published online: 16 October 2019; doi:10.1038/d41586-019-03075-5When two pharmaceutical companies turned their attention to a rare condition, they came up with different strategies for targeting RNA. Now, RNA therapies for other hereditary conditions are within the sights of the (...)

Crosslinking ionic oligomers as conformable precursors to calcium carbonate

mercredi 16 octobre 2019 par Zhaoming Liu, Changyu Shao, Biao Jin, Zhisen Zhang, Yueqi Zhao, Xurong Xu, Ruikang Tang
Nature, Published online: 16 October 2019; doi:10.1038/s41586-019-1645-xThe crosslinking of oligomeric precursors, controlled by a capping agent, enables the production of moulded crystalline calcium carbonate with continuous (...)

Reply to: Reversion after replacement of mitochondrial DNA

mercredi 16 octobre 2019 par Eunju Kang, Amy Koski, Paula Amato, Dmitry Temiakov, Shoukhrat Mitalipov
Nature, Published online: 16 October 2019; doi:10.1038/s41586-019-1624-2Reply to: Reversion after replacement of mitochondrial DNA

Altered chromosomal topology drives oncogenic programs in SDH-deficient GIST

mercredi 16 octobre 2019 par William A Flavahan, Yotam Drier, Sarah E. Johnstone, Matthew L. Hemming, Daniel R. Tarjan, Esmat Hegazi, Sarah J. Shareef, Nauman M. Javed, Chandrajit P. Raut, Benjamin K. Eschle, Prafulla C. Gokhale, Jason L. Hornick, Ewa T. Sicinska, George D. Demetri, Bradley E. Bernstein
Nature, Published online: 16 October 2019; doi:10.1038/s41586-019-1668-3Altered chromosomal topology drives oncogenic programs in SDH-deficient GIST

Sounds of a supersolid detected in dipolar atomic gases for the first time

mercredi 16 octobre 2019 par Sean M. Mossman
Nature, Published online: 16 October 2019; doi:10.1038/d41586-019-03045-xUltracold gases of dipolar atoms can exhibit fluid and crystalline oscillations at the same time, illuminating the ways in which different kinds of sound propagate in the quantum state of matter known as a (...)

Subducting carbon

mercredi 16 octobre 2019 par Terry Plank, Craig E. Manning
Nature, Published online: 16 October 2019; doi:10.1038/s41586-019-1643-zThe processes that control the movement of carbon from microfossils on the seafloor to erupting volcanoes and deep diamonds, in a cycle driven by plate tectonics, are (...)

Podcast: Mapping childhood mortality, and evolving ‘de novo’ genes

mercredi 16 octobre 2019
Nature, Published online: 16 October 2019; doi:10.1038/d41586-019-03144-9Listen to the latest from the world of science, with Benjamin Thompson and Shamini Bundell.

Protect the census

mercredi 16 octobre 2019
Nature, Published online: 16 October 2019; doi:10.1038/d41586-019-03116-zThe humble census risks becoming a casualty of the rush to embrace big data. But it has the potential to save lives.

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