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UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis

mercredi 26 juin 2019 par Xiongjun Wang, Ruilong Liu, Wencheng Zhu, Huiying Chu, Hua Yu, Ping Wei, Xueyuan Wu, Hongwen Zhu, Hong Gao, Ji Liang, Guohui Li, Weiwei Yang
Nature, Published online: 26 June 2019; doi:10.1038/s41586-019-1340-yUDP-glucose has a tumour-suppressive role by inhibiting the association between HuR and SNAI1 mRNA, whereas UGDH-mediated metabolism of UDP-glucose leads to increased SNAI1 mRNA stability and expression, thereby promoting (...)

Reply to: Can lasers really refrigerate CdS nanobelts?

mercredi 26 juin 2019 par Jun Zhang, Dehui Li, Qihua Xiong
Nature, Published online: 26 June 2019; doi:10.1038/s41586-019-1270-8Reply to: Can lasers really refrigerate CdS nanobelts?

Podcast: Callused feet, and protein-based archaeology

mercredi 26 juin 2019
Nature, Published online: 26 June 2019; doi:10.1038/d41586-019-02012-wHear the latest science news, brought to you by Benjamin Thompson and Shamini Bundell.

Lessons learnt from doing research amid a humanitarian crisis

mercredi 26 juin 2019 par Jack Leeming
Nature, Published online: 26 June 2019; doi:10.1038/d41586-019-01989-8Carrying on with data collection and model creation can be harrowing, but there are rewards in the chance to make a difference.

Doctors at many stem-cell clinics don’t have relevant training

mercredi 26 juin 2019 par Nic Fleming
Nature, Published online: 26 June 2019; doi:10.1038/d41586-019-01999-6Few US clinics offering unproven treatments employ physicians with expertise in all the conditions they offer to treat, finds survey.

Reinvestigation of a robotically revealed reaction

mercredi 26 juin 2019 par Jonathan K. Sader, Jeremy E. Wulff
Nature, Published online: 26 June 2019; doi:10.1038/s41586-019-1176-5Reinvestigation of a robotically revealed reaction

Trading in futures

mercredi 26 juin 2019 par S. R. Algernon
Nature, Published online: 26 June 2019; doi:10.1038/d41586-019-01990-1A sound investment?

Mars methane spike, stem-cell clinics and India’s space plans

mercredi 26 juin 2019
Nature, Published online: 26 June 2019; doi:10.1038/d41586-019-01984-zThe week in science: 21–27 June 2019.

Gene expression across mammalian organ development

mercredi 26 juin 2019 par Margarida Cardoso-Moreira, Jean Halbert, Delphine Valloton, Britta Velten, Chunyan Chen, Yi Shao, Angélica Liechti, Kelly Ascenção, Coralie Rummel, Svetlana Ovchinnikova, Pavel V. Mazin, Ioannis Xenarios, Keith Harshman, Matthew Mort, David N. Cooper, Carmen Sandi, Michael J. Soares, Paula G. Ferreira, Sandra Afonso, Miguel Carneiro, James M. A. Turner, John L. VandeBerg, Amir Fallahshahroudi, Per Jensen, Rüdiger Behr, Steven Lisgo, Susan Lindsay, Philipp Khaitovich, Wolfgang Huber, Julie Baker, Simon Anders, Yong E. Zhang, Henrik Kaessmann
Nature, Published online: 26 June 2019; doi:10.1038/s41586-019-1338-5The transcriptomes of seven major organs across developmental stages from several mammalian species are used for comparative analyses of gene expression and evolution across organ (...)

Publisher Correction: DNA damage detection in nucleosomes involves DNA register shifting

mercredi 26 juin 2019 par Syota Matsumoto, Simone Cavadini, Richard D. Bunker, Ralph S. Grand, Alessandro Potenza, Julius Rabl, Junpei Yamamoto, Andreas D. Schenk, Dirk Schübeler, Shigenori Iwai, Kaoru Sugasawa, Hitoshi Kurumizaka, Nicolas H. Thomä
Nature, Published online: 26 June 2019; doi:10.1038/s41586-019-1343-8Publisher Correction: DNA damage detection in nucleosomes involves DNA register shifting

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