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Sustainable development will falter without data

mercredi 17 juillet 2019 par Jessica Espey
Nature, Published online: 17 July 2019; doi:10.1038/d41586-019-02139-wUnless governments establish competent monitoring systems, the world will not reach the UN Sustainable Development Goals, says Jessica Espey.

Conformation space of a heterodimeric ABC exporter under turnover conditions

mercredi 17 juillet 2019 par Susanne Hofmann, Dovile Januliene, Ahmad R. Mehdipour, Christoph Thomas, Erich Stefan, Stefan Brüchert, Benedikt T. Kuhn, Eric R. Geertsma, Gerhard Hummer, Robert Tampé, Arne Moeller
Nature, Published online: 17 July 2019; doi:10.1038/s41586-019-1391-0Eight cryo-electron microscopy structures of the ATP-binding cassette exporter TmrAB under turnover conditions characterize the entire transport cycle in a lipid (...)

Holistic prediction of enantioselectivity in asymmetric catalysis

mercredi 17 juillet 2019 par Jolene P. Reid, Matthew S. Sigman
Nature, Published online: 17 July 2019; doi:10.1038/s41586-019-1384-zA workflow for deriving statistical models of one set of reactions that can be used to predict related reactions is presented, facilitating catalyst and enantioselective reaction (...)

Giant thermal Hall conductivity in the pseudogap phase of cuprate superconductors

mercredi 17 juillet 2019 par G. Grissonnanche, A. Legros, S. Badoux, E. Lefrançois, V. Zatko, M. Lizaire, F. Laliberté, A. Gourgout, J.-S. Zhou, S. Pyon, T. Takayama, H. Takagi, S. Ono, N. Doiron-Leyraud, L. Taillefer
Nature, Published online: 17 July 2019; doi:10.1038/s41586-019-1375-0The so-called pseudogap phase in hole-doped cuprate superconductors is associated with an unusually large thermal Hall effect that attains unprecedented levels as the parent Mott insulator is (...)

Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice

mercredi 17 juillet 2019 par Diana Matheoud, Tyler Cannon, Aurore Voisin, Anna-Maija Penttinen, Lauriane Ramet, Ahmed M. Fahmy, Charles Ducrot, Annie Laplante, Marie-Josée Bourque, Lei Zhu, Romain Cayrol, Armelle Le Campion, Heidi M. McBride, Samantha Gruenheid, Louis-Eric Trudeau, Michel Desjardins
Nature, Published online: 17 July 2019; doi:10.1038/s41586-019-1405-yIn mice lacking PINK1, bacterial infection in the intestine results in mitochondrial antigen presentation and generation of CD8+ T cells, and infected mice develop motor impairments, suggesting that PINK1 suppresses (...)

Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion

mercredi 17 juillet 2019 par Anna M. Paczulla, Kathrin Rothfelder, Simon Raffel, Martina Konantz, Julia Steinbacher, Hui Wang, Claudia Tandler, Marcelle Mbarga, Thorsten Schaefer, Mattia Falcone, Eva Nievergall, Daniela Dörfel, Pauline Hanns, Jakob R. Passweg, Christoph Lutz, Juerg Schwaller, Robert Zeiser, Bruce R. Blazar, Michael A. Caligiuri, Stephan Dirnhofer, Pontus Lundberg, Lothar Kanz, Leticia Quintanilla-Martinez, Alexander Steinle, Andreas Trumpp, Helmut R. Salih, Claudia Lengerke
Nature, Published online: 17 July 2019; doi:10.1038/s41586-019-1410-1Leukaemic stem cells in acute myeloid leukaemia are defined by a lack of expression of NKG2D ligands, which mediates their ability to evade surveillance by NK (...)

Incompatible and sterile insect techniques combined eliminate mosquitoes

mercredi 17 juillet 2019 par Xiaoying Zheng, Dongjing Zhang, Yongjun Li, Cui Yang, Yu Wu, Xiao Liang, Yongkang Liang, Xiaoling Pan, Linchao Hu, Qiang Sun, Xiaohua Wang, Yingyang Wei, Jian Zhu, Wei Qian, Ziqiang Yan, Andrew G. Parker, Jeremie R. L. Gilles, Kostas Bourtzis, Jérémy Bouyer, Moxun Tang, Bo Zheng, Jianshe Yu, Julian Liu, Jiajia Zhuang, Zhigang Hu, Meichun Zhang, Jun-Tao Gong, Xiao-Yue Hong, Zhoubing Zhang, Lifeng Lin, Qiyong Liu, Zhiyong Hu, Zhongdao Wu, Luke Anthony Baton, Ary A. Hoffmann, Zhiyong Xi
Nature, Published online: 17 July 2019; doi:10.1038/s41586-019-1407-9A field trial succeeded in eliminating populations of the mosquito Aedes albopictus through inundative mass release of incompatible Wolbachia-infected males, which were also irradiated to sterilize any accidentally-released (...)

Visualizing electrostatic gating effects in two-dimensional heterostructures

mercredi 17 juillet 2019 par Paul V. Nguyen, Natalie C. Teutsch, Nathan P. Wilson, Joshua Kahn, Xue Xia, Abigail J. Graham, Viktor Kandyba, Alessio Giampietri, Alexei Barinov, Gabriel C. Constantinescu, Nelson Yeung, Nicholas D. M. Hine, Xiaodong Xu, David H. Cobden, Neil R. Wilson
Nature, Published online: 17 July 2019; doi:10.1038/s41586-019-1402-1Changes in the electronic states of two-dimensional semiconductor devices resulting from electrical gating can be monitored directly using micrometre-scale angle-resolved photoemission (...)

Estimating and tracking the remaining carbon budget for stringent climate targets

mercredi 17 juillet 2019 par Joeri Rogelj, Piers M. Forster, Elmar Kriegler, Christopher J. Smith, Roland Séférian
Nature, Published online: 17 July 2019; doi:10.1038/s41586-019-1368-zA method of tracking changes in estimates of the remaining carbon budget over time should help to reconcile differences between these estimates and clarify their usefulness for setting emission reduction (...)

Ebola spread, Turing honour and mosquito-eradication trial

mercredi 17 juillet 2019
Nature, Published online: 17 July 2019; doi:10.1038/d41586-019-02140-3The week in science: 12–18 July 2019.

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